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Surfactant Associated Protein A2 (SPA2)

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SFTPA2B; COLEC5; SP2A; SPA1 beta; SP-A2; SPAII; Collectin-5; Pulmonary Surfactant Protein A2; 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein

Surfactant Associated Protein A2 (SPA2)
CCC D521
HGNC 10799
MGI 109518
PubMed 16087740
UniProt Q8IWL1
Wiki SFTPA2B
Pulmonary Surfactant Associated Protein A2 is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.SPA2 transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD521Hu01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD521Hu01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Surfactant Associated Protein A2 (SPA2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Surfactant Associated Protein A2 (SPA2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Surfactant Associated Protein A2 (SPA2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD521Ra01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD521Ra01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
Assay Kits SED521Ra ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein."J. Biol. Chem. 261:9029-9033(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of a second human pulmonary surfactant-associated protein SP-A gene."Am. J. Respir. Cell Mol. Biol. 6:446-452(1992) [PubMed] [Europe PMC] [Abstract]
  3. "Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene."Am. J. Physiol. 299:L523-L534(2010) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Studies of the structure of lung surfactant protein SP-A."Am. J. Physiol. 257:L421-L429(1989) [PubMed] [Europe PMC] [Abstract]
  7. "Genetics of the hydrophilic surfactant proteins A and D."Biochim. Biophys. Acta 1408:312-322(1998) [PubMed] [Europe PMC] [Abstract]
  8. "Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer."Am. J. Hum. Genet. 84:52-59(2009) [PubMed] [Europe PMC] [Abstract]