Cyclin B2 (CCNB2)

[Edit]

CCN-B2; G2/mitotic-specific cyclin-B2

Cyclin B2 (CCNB2)
Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle until mitosis, where they fall abruptly due to degradation.
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD265Hu01 Recombinant Cyclin B2 (CCNB2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD265Hu01 Polyclonal Antibody to Cyclin B2 (CCNB2) WB; IHC; ICC; IP.
MAD265Hu21 Monoclonal Antibody to Cyclin B2 (CCNB2) WB; IHC; ICC; IP.
Assay Kits SED265Hu ELISA Kit for Cyclin B2 (CCNB2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cyclin B2 (CCNB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cyclin B2 (CCNB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cyclin B2 (CCNB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cyclin B2 (CCNB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cyclin B2 (CCNB2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cyclin B2 (CCNB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cyclin B2 (CCNB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cyclin B2 (CCNB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cyclin B2 (CCNB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cyclin B2 (CCNB2) ELISA Kit Customized Service Offer
  1. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]