Syntenin 2 (ST2)

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SDCBP2; SITAC18; Syndecan Binding Protein 2

Syntenin 2 (ST2)
Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans.Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.Syndecan-2 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD171Hu01 Recombinant Syntenin 2 (ST2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD171Hu01 Polyclonal Antibody to Syntenin 2 (ST2) WB; IHC; ICC; IP.
MAD171Hu21 Monoclonal Antibody to Syntenin 2 (ST2) WB; IHC; ICC; IP.
Assay Kits SED171Hu ELISA Kit for Syntenin 2 (ST2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Syntenin 2 (ST2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Syntenin 2 (ST2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Syntenin 2 (ST2) Polyclonal Antibody Customized Service Offer
Assay Kits SED171Mu ELISA Kit for Syntenin 2 (ST2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Syntenin 2 (ST2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Syntenin 2 (ST2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Syntenin 2 (ST2) Polyclonal Antibody Customized Service Offer
Assay Kits SED171Ra ELISA Kit for Syntenin 2 (ST2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity."J. Biol. Chem. 276:10646-10654(2001) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]