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T-Cell Surface Glycoprotein CD3 Gamma (CD3g)

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T3G; CD3-G; CD3g Molecule,Gamma(CD3-TCR Complex); CD3-GAMMA

T-Cell Surface Glycoprotein CD3 Gamma (CD3g)
CCC D118
HGNC 1675
MGI 88333
PubMed 1829960
RGD 1307718
UniProt P09693
Wiki CD3G
CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.
T-Cell Surface Glycoprotein CD3 Gamma is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD118Hu01 Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Positive Control; Immunogen; SDS-PAGE; WB.
RPD118Hu02 Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Positive Control; Immunogen; SDS-PAGE; WB.
RPD118Hu03 Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD118Hu23 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB; IHC; ICC; IP.
MAD118Hu21 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB
MAD118Hu24 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB
MAD118Hu22 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) ELISA Kit Customized Service Offer
  1. "Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits."EMBO J. 5:1799-1808(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Physical linkage of three CD3 genes on human chromosome 11."EMBO J. 6:2953-2957(1987) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Dephosphorylation of the human T lymphocyte CD3 antigen."Eur. J. Biochem. 181:55-65(1989) [PubMed] [Europe PMC] [Abstract]
  5. "The human T3 gamma chain is phosphorylated at serine 126 in response to T lymphocyte activation."J. Biol. Chem. 262:10918-10921(1987) [PubMed] [Europe PMC] [Abstract]
  6. "A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains."Cell 69:1143-1157(1992) [PubMed] [Europe PMC] [Abstract]
  7. "Brief report: primary immunodeficiency caused by mutations in the gene encoding the CD3-gamma subunit of the T-lymphocyte receptor."N. Engl. J. Med. 327:529-533(1992) [PubMed] [Europe PMC] [Abstract]
  8. "Differential biological role of CD3 chains revealed by human immunodeficiencies."J. Immunol. 178:2556-2564(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3."Proc. Natl. Acad. Sci. U.S.A. 101:7675-7680(2004) [PubMed] [Europe PMC] [Abstract]