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Glycyl tRNA Synthetase (GARS)

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CMT2D; CMT2-D; DSMAV; GlyRS; SMAD1; EJ; Charcot-Marie-Tooth Neuropathy 2D; Glycine tRNA Ligase; Diadenosine tetraphosphate synthetase; AP-4-A synthetase

Glycyl tRNA Synthetase (GARS)
CCC C996
HGNC 4162
MGI 2449057
PubMed 19412816
RGD 1307856
UniProt P41250
Wiki GARS
Glycyl-tRNA synthetase isone of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.Defects in GARS are the cause of distal spinal muscular atrophy type V (DSMA-V). DSMA-V is an autosomal dominant distal hereditary motor neuropathy (dHMN) with a phenotype similar to CMTD2. The main characteristic that distinguishes these disorders is the less severe distal sensory involvement in DSMA-V patients.Defects in GARS are the cause of Charcot-Marie-Tooth disease type 2D (CMT2D)

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC996Hu01 Recombinant Glycyl tRNA Synthetase (GARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC996Hu01 Polyclonal Antibody to Glycyl tRNA Synthetase (GARS) WB; IHC; ICC/IF
MAC996Hu22 Monoclonal Antibody to Glycyl tRNA Synthetase (GARS) WB; IHC; ICC; IP.
Assay Kits SEC996Hu ELISA Kit for Glycyl tRNA Synthetase (GARS) Enzyme-linked immunosorbent assay for Antigen Detection.
AEC996Hu ELISA Kit for Anti-Glycyl tRNA Synthetase Antibody (Anti-GARS) Enzyme-linked immunosorbent assay for Antibody Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycyl tRNA Synthetase (GARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycyl tRNA Synthetase (GARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycyl tRNA Synthetase (GARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycyl tRNA Synthetase (GARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycyl tRNA Synthetase (GARS) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycyl tRNA Synthetase (GARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycyl tRNA Synthetase (GARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycyl tRNA Synthetase (GARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycyl tRNA Synthetase (GARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycyl tRNA Synthetase (GARS) ELISA Kit Customized Service Offer
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