Secernin 1 (SCRN1)
Secernin-1 is a protein encoded by the SCRN1 gene. is an archaic English term meaning 'secrete'.Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium.Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium
Secernin 1, a novel 50-kDa cytosolic protein that appears to be involved in the regulation of exocytosis from peritoneal mast cells. Secernin 1 increases both the extent of secretion and increases the sensitivity of mast cells to stimulation with calcium.This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC836Hu01 Recombinant Secernin 1 (SCRN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC836Hu01 Polyclonal Antibody to Secernin 1 (SCRN1) WB,IHC
Assay Kits SEC836Hu ELISA Kit for Secernin 1 (SCRN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC836Mu01 Recombinant Secernin 1 (SCRN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC836Mu01 Polyclonal Antibody to Secernin 1 (SCRN1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Secernin 1 (SCRN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Secernin 1 (SCRN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Secernin 1 (SCRN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Secernin 1 (SCRN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Secernin 1 (SCRN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Secernin 1 (SCRN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Secernin 1 (SCRN1) ELISA Kit Customized Service Offer
  1. "Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray."Cancer Sci. 97:411-419(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 3:17-24(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]