N-Terminal Pro-C-Type Natriuretic Peptide (NT-ProCNP)

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N-CNP

N-Terminal Pro-C-Type Natriuretic Peptide (NT-ProCNP)

Natriuretic peptide precursor C is cleaved to the 22 amino acid peptide C-type natriuretic peptide (CNP). Unlike ANP and BNP, CNP does not have direct natriuretic activity. This is because CNP is a selective agonist for the B-type natriuretic receptor (NPRB) whereas ANP and BNP are selective for NPRA.

Recent evidence from rodents and humans shows that C-type natriuretic peptide (CNP) plays an essential role in endochondral bone growth. A stable product of proCNP, amino-terminal proCNP (NT-proCNP), which unlike CNP is readily measurable in human and ovine plasma. NT-proCNP levels in blood show a strong association with growth velocity and markers of bone formation and may well serve as a useful marker of growth plate activity in humans and other mammals.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of N-Terminal Pro-C-Type Natriuretic Peptide (NT-ProCNP) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to N-Terminal Pro-C-Type Natriuretic Peptide (NT-ProCNP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to N-Terminal Pro-C-Type Natriuretic Peptide (NT-ProCNP) Polyclonal Antibody Customized Service Offer
Assay Kits CEC673Hu ELISA Kit for N-Terminal Pro-C-Type Natriuretic Peptide (NT-ProCNP) Enzyme-linked immunosorbent assay for Antigen Detection.