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Ubiquitin Associated Protein 1 (UBAP1)

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NAG20; UAP; UBAP; Nasopharyngeal carcinoma-associated gene 20 protein

Ubiquitin Associated Protein 1 (UBAP1)
CCC C583
HGNC 12461
MGI 2149543
PubMed 21757351
RGD 1305186
UniProt Q9NZ09
Wiki UBAP1
Ubiquitin-associated protein 1 is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle.
This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas.Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC583Hu01 Recombinant Ubiquitin Associated Protein 1 (UBAP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC583Hu01 Polyclonal Antibody to Ubiquitin Associated Protein 1 (UBAP1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ubiquitin Associated Protein 1 (UBAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Associated Protein 1 (UBAP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC583Mu01 Recombinant Ubiquitin Associated Protein 1 (UBAP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC583Mu01 Polyclonal Antibody to Ubiquitin Associated Protein 1 (UBAP1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ubiquitin Associated Protein 1 (UBAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Associated Protein 1 (UBAP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Associated Protein 1 (UBAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Associated Protein 1 (UBAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Associated Protein 1 (UBAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Associated Protein 1 (UBAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Associated Protein 1 (UBAP1) ELISA Kit Customized Service Offer
  1. "Isolation and characterization of a novel cDNA, UBAP1, derived from the tumor suppressor locus in human chromosome 9p21-22."J. Cancer Res. Clin. Oncol. 127:613-618(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting."Curr. Biol. 21:1245-1250(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Solution structure of UBA domain of human ubiquitin associated protein 1 (UBAP1)."Submitted (NOV-2004) to the PDB data bank
  9. "The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain."Structure 20:414-428(2012) [PubMed] [Europe PMC] [Abstract]