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Gastrin-releasing peptide, also known as GRP, is an important regulatory molecule that has been implicated in a number of physiological and pathophysiological processes in the human organism.
The corresponding human gene has been identified. This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its 148 amino acid (AA) preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 AA gastrin-releasing peptide or the 10 AA neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.
The corresponding human gene has been identified. This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its 148 amino acid (AA) preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 AA gastrin-releasing peptide or the 10 AA neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC506Hu01 | Recombinant Gastrin Releasing Peptide (GRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPC506Hu21 | OVA Conjugated Gastrin Releasing Peptide (GRP) | Immunogen; SDS-PAGE; WB. | |
| CPC506Hu11 | BSA Conjugated Gastrin Releasing Peptide (GRP) | Immunogen; SDS-PAGE; WB. | |
| SPC506Hu01 | Synthetic Gastrin Releasing Peptide (GRP) | Immunogen; Blocking Peptide. | |
| Antibodies | PAC506Hu01 | Polyclonal Antibody to Gastrin Releasing Peptide (GRP) | WB; IHC; ICC; IP. |
| MAC506Hu21 | Monoclonal Antibody to Gastrin Releasing Peptide (GRP) | WB; IHC; ICC; IP. | |
| PAC506Hu08 | Polyclonal Antibody to Gastrin Releasing Peptide (GRP) | WB; IHC; ICC; IP. | |
| Assay Kits | CEC506Hu | ELISA Kit for Gastrin Releasing Peptide (GRP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | CPC506Mu21 | OVA Conjugated Gastrin Releasing Peptide (GRP) | Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC506Mu01 | Polyclonal Antibody to Gastrin Releasing Peptide (GRP) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Gastrin Releasing Peptide (GRP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Gastrin Releasing Peptide (GRP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | CPC506Ra21 | OVA Conjugated Gastrin Releasing Peptide (GRP) | Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC506Ra01 | Polyclonal Antibody to Gastrin Releasing Peptide (GRP) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Gastrin Releasing Peptide (GRP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Gastrin Releasing Peptide (GRP) | ELISA Kit Customized Service Offer |
- "Two prohormones for gastrin-releasing peptide are encoded by two mRNAs differing by 19 nucleotides."Proc. Natl. Acad. Sci. U.S.A. 83:19-23(1986) [PubMed] [Europe PMC] [Abstract]
- "Posttranslational processing of endogenous and of baculovirus-expressed human gastrin-releasing peptide precursor."Mol. Cell. Biol. 8:3129-3135(1988) [PubMed] [Europe PMC] [Abstract]
- "Expression of the gastrin-releasing peptide gene in human small cell lung cancer. Evidence for alternative processing resulting in three distinct mRNAs."J. Biol. Chem. 261:2451-2457(1986) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence and analysis of human chromosome 18." Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]