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Decorin is a proteoglycan on average 90 - 140 kilodaltons (kD) in size.It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly.
Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta).
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC127Hu01 | Recombinant Decorin (DCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPC127Hu02 | Recombinant Decorin (DCN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAC127Hu01 | Polyclonal Antibody to Decorin (DCN) | WB; IHC; ICC; IP. |
| MAC127Hu22 | Monoclonal Antibody to Decorin (DCN) | WB; IHC; ICC; IP. | |
| PAC127Hu02 | Polyclonal Antibody to Decorin (DCN) | WB; IHC; ICC; IP. | |
| LAC127Hu71 | Biotin-Linked Polyclonal Antibody to Decorin (DCN) | WB; IHC; ICC. | |
| Assay Kits | SEC127Hu | ELISA Kit for Decorin (DCN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Decorin (DCN) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Decorin (DCN) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Decorin (DCN) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Decorin (DCN) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Decorin (DCN) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Decorin (DCN) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Decorin (DCN) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Decorin (DCN) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Decorin (DCN) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Decorin (DCN) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Decorin (DCN) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Decorin (DCN) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Decorin (DCN) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Decorin (DCN) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Decorin (DCN) | ELISA Kit Customized Service Offer |
- "Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA."Proc. Natl. Acad. Sci. U.S.A. 83:7683-7687(1986) [PubMed] [Europe PMC] [Abstract]
- "Human decorin gene: intron-exon junctions and chromosomal localization."Genomics 15:161-168(1993) [PubMed] [Europe PMC] [Abstract]
- "The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5' untranslated region, and mapping of the gene to chromosome 12q23."Genomics 15:146-160(1993) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Dermatan sulphate proteoglycans of human articular cartilage. The properties of dermatan sulphate proteoglycans I and II."Biochem. J. 262:823-827(1989) [PubMed] [Europe PMC] [Abstract]
- "Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone."J. Biol. Chem. 262:9702-9708(1987) [PubMed] [Europe PMC] [Abstract]
- "Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene."Invest. Ophthalmol. Vis. Sci. 46:420-426(2005) [PubMed] [Europe PMC] [Abstract]
- "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]