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Integrin Alpha 11 (ITGa11)

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ITG-A11

Integrin Alpha 11 (ITGa11)
CCC C097
HGNC 6136
MGI 2442114
PubMed 12392762
RGD 1311711
UniProt Q9UKX5
Wiki ITGA11

Integrin alpha-11 is an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form.

Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. According to one study, ITGA11 expression is increased in the anterior stroma of corneal buttons excised from the eyes affected by keratoconus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC097Hu01 Recombinant Integrin Alpha 11 (ITGa11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC097Hu01 Polyclonal Antibody to Integrin Alpha 11 (ITGa11) WB,IHC
MAC097Hu22 Monoclonal Antibody to Integrin Alpha 11 (ITGa11) WB; IHC; ICC; IP.
MAC097Hu21 Monoclonal Antibody to Integrin Alpha 11 (ITGa11) WB; IHC; ICC; IP.
Assay Kits SEC097Hu ELISA Kit for Integrin Alpha 11 (ITGa11) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC097Mu01 Recombinant Integrin Alpha 11 (ITGa11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC097Mu01 Polyclonal Antibody to Integrin Alpha 11 (ITGa11) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Integrin Alpha 11 (ITGa11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrin Alpha 11 (ITGa11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Integrin Alpha 11 (ITGa11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Integrin Alpha 11 (ITGa11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Integrin Alpha 11 (ITGa11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Integrin Alpha 11 (ITGa11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrin Alpha 11 (ITGa11) ELISA Kit Customized Service Offer
  1. "Cloning, sequence analysis, and chromosomal localization of the novel human integrin alpha11 subunit (ITGA11)."Genomics 60:179-187(1999) [PubMed] [Europe PMC] [Abstract]
  2. "cDNA cloning and chromosomal localization of human alpha(11) integrin. A collagen-binding, I domain-containing, beta(1)-associated integrin alpha-chain present in muscle tissues."J. Biol. Chem. 274:25735-25742(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  4. "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins."J. Cell Biol. 173:767-780(2006) [PubMed] [Europe PMC] [Abstract]
  5. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]