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S100 Calcium Binding Protein A3 (S100A3)

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S100E; S100-A3

S100 Calcium Binding Protein A3 (S100A3)
CCC C015
HGNC 10493
MGI 1338849
PubMed 9804353
RGD 620260
UniProt P33764
Wiki S100A3

S100 calcium binding protein A3 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.

This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC015Hu01 Recombinant S100 Calcium Binding Protein A3 (S100A3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC015Hu01 Polyclonal Antibody to S100 Calcium Binding Protein A3 (S100A3) WB; IHC; ICC; IP.
LAC015Hu71 Biotin-Linked Polyclonal Antibody to S100 Calcium Binding Protein A3 (S100A3) WB; IHC; ICC.
MAC015Hu21 Monoclonal Antibody to S100 Calcium Binding Protein A3 (S100A3) WB,IHC
Assay Kits n/a CLIA Kit for S100 Calcium Binding Protein A3 (S100A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for S100 Calcium Binding Protein A3 (S100A3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant S100 Calcium Binding Protein A3 (S100A3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to S100 Calcium Binding Protein A3 (S100A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to S100 Calcium Binding Protein A3 (S100A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for S100 Calcium Binding Protein A3 (S100A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for S100 Calcium Binding Protein A3 (S100A3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC015Ra01 Recombinant S100 Calcium Binding Protein A3 (S100A3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC015Ra01 Polyclonal Antibody to S100 Calcium Binding Protein A3 (S100A3) WB; IHC; ICC; IP.
LAC015Ra71 Biotin-Linked Polyclonal Antibody to S100 Calcium Binding Protein A3 (S100A3) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for S100 Calcium Binding Protein A3 (S100A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for S100 Calcium Binding Protein A3 (S100A3) ELISA Kit Customized Service Offer
  1. "Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E."Proc. Natl. Acad. Sci. U.S.A. 90:6547-6551(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Probing the structure of the human Ca2+- and Zn2+-binding protein S100A3: spectroscopic investigations of its transition metal ion complexes, and three-dimensional structural model."Biochim. Biophys. Acta 1448:264-276(1998) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of the cysteine-rich calcium-binding S100A3 protein from human hair cuticles."Biochem. Biophys. Res. Commun. 299:857-862(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Specific citrullination causes assembly of a globular S100A3 homotetramer: a putative Ca2+ modulator matures human hair cuticle."J. Biol. Chem. 283:5004-5013(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Metal-free MIRAS phasing: structure of apo-S100A3."Acta Crystallogr. D 58:1255-1261(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Refined crystal structures of human Ca(2+)/Zn(2+)-binding S100A3 protein characterized by two disulfide bridges."J. Mol. Biol. 408:477-490(2011) [PubMed] [Europe PMC] [Abstract]