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IL-17F has been shown to stimulate prolifertion and activation of T cells and PBMCs, to inhibit angiogenesis as well as to regulate cartilage matrix turnover. This recombinant IL-17F is a homodimeric protein with a total weight of 30.1kDa containing two 134 amino acid residue chains.Using nested RACE PCR with leukocyte-anchored cDNA, Starnes et al. (2001) isolated an IL17F cDNA encoding a 153-amino acid protein that shares 40% homology with IL17.
In addition to the 2 invariant disulfide bonds found in other members of the IL17 family, IL17F contains a signal peptide with an extra cys-cys pair that could function as an extra disulfide bond. Expression of IL17F could not be identified by Northern blot analysis. RT-PCR analysis detected expression in activated, but not resting, CD4+ T cells and activated monocytes.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB955Hu01 | Recombinant Interleukin 17F (IL17F) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB955Hu01 | Active Interleukin 17F (IL17F) | Cell culture; Activity Assays. | |
| EPB955Hu61 | Eukaryotic Interleukin 17F (IL17F) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APB955Hu61 | Active Interleukin 17F (IL17F) | Cell culture; Activity Assays. | |
| Antibodies | PAB955Hu01 | Polyclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC; IP. |
| MAB955Hu22 | Monoclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC; IP. | |
| LAB955Hu71 | Biotin-Linked Polyclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC. | |
| LAB955Hu81 | FITC-Linked Polyclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC; IF. | |
| MAB955Hu21 | Monoclonal Antibody to Interleukin 17F (IL17F) | WB. | |
| Assay Kits | SEB955Hu | ELISA Kit for Interleukin 17F (IL17F) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB955Hu | CLIA Kit for Interleukin 17F (IL17F) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB955Mu01 | Recombinant Interleukin 17F (IL17F) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB955Mu02 | Recombinant Interleukin 17F (IL17F) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB955Mu01 | Polyclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC; IP. |
| PAB955Mu02 | Polyclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB955Mu | ELISA Kit for Interleukin 17F (IL17F) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB955Mu | CLIA Kit for Interleukin 17F (IL17F) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB955Ra01 | Recombinant Interleukin 17F (IL17F) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB955Ra01 | Polyclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC; IP. |
| MAB955Ra21 | Monoclonal Antibody to Interleukin 17F (IL17F) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB955Ra | ELISA Kit for Interleukin 17F (IL17F) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB955Ra | CLIA Kit for Interleukin 17F (IL17F) | Chemiluminescent immunoassay for Antigen Detection. |
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