Cytokeratin 13 (CK13)

Keratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains.

This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB875Hu01 Recombinant Cytokeratin 13 (CK13) Positive Control; Immunogen; SDS-PAGE; WB.
RPB875Hu02 Recombinant Cytokeratin 13 (CK13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB875Hu01 Polyclonal Antibody to Cytokeratin 13 (CK13) WB; IHC; ICC; IP.
MAB875Hu22 Monoclonal Antibody to Cytokeratin 13 (CK13) WB; IHC; ICC; IP.
Assay Kits SEB875Hu ELISA Kit for Cytokeratin 13 (CK13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytokeratin 13 (CK13) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytokeratin 13 (CK13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytokeratin 13 (CK13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytokeratin 13 (CK13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytokeratin 13 (CK13) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB875Ra01 Recombinant Cytokeratin 13 (CK13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB875Ra01 Polyclonal Antibody to Cytokeratin 13 (CK13) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cytokeratin 13 (CK13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytokeratin 13 (CK13) ELISA Kit Customized Service Offer
  1. "Sequence of a human keratin 13 specific cDNA encompassing coil 1B through the 3' end."Biochem. Biophys. Res. Commun. 162:1522-1527(1989) [PubMed] [Europe PMC] [Abstract]
  2. "The N-, but not the C-terminal domains of human keratins 13 and 15 are closely related."Nucleic Acids Res. 17:7984-7984(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Synthesis of cytokeratin 13, a component characteristic of internal stratified epithelia, is not induced in human epidermal tumors."Differentiation 42:111-123(1989) [PubMed] [Europe PMC] [Abstract]
  4. "Isolation, sequence and expression of the gene encoding human keratin 13."Gene 215:269-279(1998) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]