Interleukin 2 Receptor Alpha (IL2Ra)

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CD25; IL2R-a; IL2-RA; IDDM10; IL2R; TCGFR; p55; TAC antigen

Interleukin 2 Receptor Alpha (IL2Ra)

CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2.CD25 expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.

Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is currently unknown.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB837Hu01 Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
APB837Hu61 Active Interleukin 2 Receptor Alpha (IL2Ra) Cell culture; Activity Assays.
EPB837Hu61 Eukaryotic Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB837Hu01 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; ICC; IHC-P; IHC-F; ELISA.
MAB837Hu22 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Hu26 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Hu21 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Hu23 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Hu24 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Hu27 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Hu29 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Hu25 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
Assay Kits SEB837Hu ELISA Kit for Interleukin 2 Receptor Alpha (IL2Ra) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB837Mu01 Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
RPB837Mu02 Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
APB837Mu02 Active Interleukin 2 Receptor Alpha (IL2Ra) Cell culture; Activity Assays.
Antibodies PAB837Mu02 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
PAB837Mu01 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
Assay Kits SEB837Mu ELISA Kit for Interleukin 2 Receptor Alpha (IL2Ra) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB837Ra01 Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
RPB837Ra02 Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB837Ra01 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
PAB837Ra02 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
LAB837Ra71 Biotin-Linked Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC.
LAB837Ra81 FITC-Linked Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IF.
PAB837Ra03 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
Assay Kits SEB837Ra ELISA Kit for Interleukin 2 Receptor Alpha (IL2Ra) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interleukin 2 Receptor Alpha (IL2Ra) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 2 Receptor Alpha (IL2Ra) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB837Po01 Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB837Po01 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 2 Receptor Alpha (IL2Ra) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 2 Receptor Alpha (IL2Ra) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB837Bo01 Recombinant Interleukin 2 Receptor Alpha (IL2Ra) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB837Bo01 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
MAB837Bo21 Monoclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) WB; IHC; ICC; IP.
Assay Kits SEB837Bo ELISA Kit for Interleukin 2 Receptor Alpha (IL2Ra) Enzyme-linked immunosorbent assay for Antigen Detection.
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  11. "Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes."Nat. Genet. 39:1074-1082(2007) [PubMed] [Europe PMC] [Abstract]