Interleukin 32 (IL32)
[Edit]NK4; TAIF; TAIFb; TAIFd; Natural Killer Cell Transcript 4; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor
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Interleukin 32 (IL-32) is a cytokine that can induce cells of the immune system (such as monocytes and macrophages) to secrete tumor necrosis factor-alpha (TNF-α) in addition to chemokines such as IL-8 and MIP-2/CXCL2.IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton.
Northern blot analysis revealed expression of a 1.0-kb transcript in activated NK and T cells, but no expression was detected in B cells or fibroblasts. Southern blot and sequence analyses indicated variable expression of NK4 in different individuals, suggesting that the NK4 gene is polymorphic. SDS-PAGE analysis showed expression of a 27-kD protein, in agreement with the predicted size.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB802Hu01 | Recombinant Interleukin 32 (IL32) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB802Hu01 | Active Interleukin 32 (IL32) | Cell culture; Activity Assays. | |
| RPB802Hu02 | Recombinant Interleukin 32 (IL32) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APB802Hu02 | Active Interleukin 32 (IL32) | Cell culture; Activity Assays. | |
| Antibodies | PAB802Hu01 | Polyclonal Antibody to Interleukin 32 (IL32) | WB; IHC; ICC; IP. |
| MAB802Hu22 | Monoclonal Antibody to Interleukin 32 (IL32) | WB; IHC; ICC; IP. | |
| PAB802Hu02 | Polyclonal Antibody to Interleukin 32 (IL32) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB802Hu | ELISA Kit for Interleukin 32 (IL32) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB802Hu | CLIA Kit for Interleukin 32 (IL32) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Interleukin 32 (IL32) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Interleukin 32 (IL32) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interleukin 32 (IL32) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Interleukin 32 (IL32) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 32 (IL32) | ELISA Kit Customized Service Offer |
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