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Oncostatin M Receptor (OSMR)

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OSMRB; IL-31RB; Oncostatin-M-specific receptor subunit beta; Interleukin-31 receptor subunit beta

Oncostatin M Receptor (OSMR)
CCC B761
HGNC 8507
MGI 1330819
PubMed 24659184
RGD 1302983
UniProt Q99650
Wiki OSMR

Oncostatin M receptor is a receptor for oncostatin M.Oncostatin M (OSM) is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 (IL6ST) as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with leukemia inhibitory factor receptor (LIFR), induces a proliferative response in permissive cells. Mosley et al. (1996) used degenerate PCR to clone a novel hematopoietin receptor which they called the oncostatin M-specific receptor beta subunit (OSMR-beta). Sequencing revealed that this gene encodes a 979-amino acid protein containing characteristic motifs of the hematopoietin receptor family.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB761Hu01 Recombinant Oncostatin M Receptor (OSMR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB761Hu01 Polyclonal Antibody to Oncostatin M Receptor (OSMR) WB; IHC; ICC; IP.
MAB761Hu22 Monoclonal Antibody to Oncostatin M Receptor (OSMR) WB; IHC; ICC; IP.
Assay Kits SEB761Hu ELISA Kit for Oncostatin M Receptor (OSMR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB761Mu01 Recombinant Oncostatin M Receptor (OSMR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB761Mu01 Polyclonal Antibody to Oncostatin M Receptor (OSMR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Oncostatin M Receptor (OSMR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oncostatin M Receptor (OSMR) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB761Ra01 Recombinant Oncostatin M Receptor (OSMR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB761Ra01 Polyclonal Antibody to Oncostatin M Receptor (OSMR) WB,IHC
Assay Kits n/a CLIA Kit for Oncostatin M Receptor (OSMR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oncostatin M Receptor (OSMR) ELISA Kit Customized Service Offer
  1. "Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation."J. Biol. Chem. 271:32635-32643(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice." Nat. Immunol. 5:752-760(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis."Am. J. Hum. Genet. 82:73-80(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis."Eur. J. Hum. Genet. 18:26-32(2010) [PubMed] [Europe PMC] [Abstract]