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Dihydropyrimidinase Like Protein 3 (DPYSL3)

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CRMP4; DRP3; ULIP; Dihydropyrimidinase-related protein 3; Collapsin response mediator protein 4; Unc-33-like phosphoprotein 1

Dihydropyrimidinase Like Protein 3 (DPYSL3)
CCC B749
HGNC 3015
MGI 1349762
PubMed 24339867
RGD 2410
UniProt Q14195
Wiki DPYSL3

  • Byk et al. (1996) isolated and characterized a novel mouse phosphoprotein with significant homology to Unc33, a protein important for neuritic outgrowth and guidance in C. elegans. The cDNA isolated from mouse brain has an open reading frame that encodes a protein of 570 amino acids with a predicted molecular mass of 61,940 Da and a theoretical pI of 6.3. This sequence shows consensus sites for several protein kinases, corroborating biochemical studies indicating the phosphorylation of partially purified ULIP with protein kinase A (PKA), casein kinase-2 , and CDC2 kinase . ULIP was found to be cytoplasmic in PC12 cells, and it exclusively associated with neurons, particularly at neuromuscular junctions. Byk et al. (1996) stated that 3 human ESTs show between 76 and 96% overall identity to the mouse ULIP sequence.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB749Hu01 Recombinant Dihydropyrimidinase Like Protein 3 (DPYSL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB749Mu01 Recombinant Dihydropyrimidinase Like Protein 3 (DPYSL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB749Mu01 Polyclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dihydropyrimidinase Like Protein 3 (DPYSL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) ELISA Kit Customized Service Offer
  1. "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution."Gene 180:157-163(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Identification and characterization of a retinoic acid-regulated human homologue of the unc-33-like phosphoprotein gene (hUlip) from neuroblastoma cells."J. Biol. Chem. 272:12195-12201(1997) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  4. , Submitted (DEC-2008) to UniProtKB
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo."J. Biol. Chem. 281:16591-16598(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]