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Fc Receptor Like Protein 5 (FCRL5)

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CD307; BXMAS1; FCRH5; IRTA2; PRO820; Fc receptor homolog 5; Immune receptor translocation-associated protein 2

Fc Receptor Like Protein 5 (FCRL5)
CCC B747
HGNC 18508
PubMed 20626413
UniProt Q96RD9
Wiki FCRL5

Fc receptor-like protein 5 is a protein encoded by the FCRL5 gene.Chromosomal abnormalities involving translocation breakpoints at 1q21-q23 are frequent in B-cell non-Hodgkin lymphoma and multiple myeloma (MM).

By cloning the breakpoints of a (1;14)(q21;q32) chromosomal translocation in the FR4 multiple myeloma cell line, followed by exon trapping and screening a spleen cDNA library, Hatzivassiliou et al. (2001) obtained cDNAs encoding 3 isoforms of IRTA1  and 4 isoforms of IRTA2. The 3 major IRTA2 mRNA isoforms (ITRA2A, ITRA2B, and ITRA2C) each have their own unique 3-prime untranslated region, and the proteins they encode share a common amino acid sequence until residue 560, including a signal peptide and 6 extracellular Ig-type domains.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fc Receptor Like Protein 5 (FCRL5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fc Receptor Like Protein 5 (FCRL5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fc Receptor Like Protein 5 (FCRL5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fc Receptor Like Protein 5 (FCRL5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fc Receptor Like Protein 5 (FCRL5) ELISA Kit Customized Service Offer
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  3. "Identification of a family of Fc receptor homologs with preferential B cell expression."Proc. Natl. Acad. Sci. U.S.A. 98:9772-9777(2001) [PubMed] [Europe PMC] [Abstract]
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  10. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]