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Protein Kinase B Beta (PKBb)

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AKT2; PKBBETA; PRKB-B; RAC-BETA; RAC-Beta Serine/Threonine-Protein Kinase; V-Akt Murine Thymoma Viral Oncogene Homolog 2

Protein Kinase B Beta (PKBb)
CCC B719
HGNC 392
MGI 104874
PubMed 12517798
RGD 2082
UniProt P31751
Wiki AKT

AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phosphorylating several known proteins. Mice lacking Akt2 have a normal body mass, but display a profound diabetic phenotype, indicating that Akt2 plays a key role in signal transduction downstream of the insulin receptor. Mice lacking Akt2 show worse outcome in breast cancer initaited by the large T antigen as well as the neu oncogene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB719Hu01 Recombinant Protein Kinase B Beta (PKBb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB719Hu01 Polyclonal Antibody to Protein Kinase B Beta (PKBb) WB,IHC,ICC/IF
MAB719Hu22 Monoclonal Antibody to Protein Kinase B Beta (PKBb) WB; IHC; ICC; IP.
Assay Kits SEB719Hu ELISA Kit for Protein Kinase B Beta (PKBb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Kinase B Beta (PKBb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Kinase B Beta (PKBb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Kinase B Beta (PKBb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Kinase B Beta (PKBb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Kinase B Beta (PKBb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB719Ra01 Recombinant Protein Kinase B Beta (PKBb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB719Ra01 Polyclonal Antibody to Protein Kinase B Beta (PKBb) WB; IHC; ICC; IP.
MAB719Ra21 Monoclonal Antibody to Protein Kinase B Beta (PKBb) WB; IHC; ICC; IP.
Assay Kits SEB719Ra ELISA Kit for Protein Kinase B Beta (PKBb) Enzyme-linked immunosorbent assay for Antigen Detection.
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