Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE)

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GSDMC; Gasdermin C; Melanoma-Derived Leucine Zipper,Extranuclear Factor

Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE)

Melanoma-derived leucine zipper extranuclear factor (MLZE) was originally isolated from a human melanoma cell line as a marker of melanoma progression . It was mapped to chromosome 8q24.1–q24.2, and its mouse homologue, Mlze, was mapped to the syntenic region in Band D1 of chromosome 15 (15D1).The human gene PRO2521 is renamed Gasdermin B; a mouse GSDMB homologue has not yet been found. Mlze, located on mouse chromosome 15, is renamed Gasdermin C1, and its human homologue located centromeric to BM-009  on chromosome 8q24.1 is renamed GSDMC. Finally, human GSDMDC1 and its mouse counterpart, Gsdmdc1, are renamed human Gasdermin D  and mouse Gasdermin D, respectively. In the phylogenetic tree in Fig. 1, the former name of each gene is shown in parentheses.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB646Hu01 Recombinant Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB646Hu01 Polyclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) WB; IHC; ICC; IP.
MAB646Hu22 Monoclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) WB; IHC; ICC; IP.
Assay Kits SEB646Hu ELISA Kit for Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) ELISA Kit Customized Service Offer
  1. "Structure, expression and chromosome mapping of MLZE, a novel gene which is preferentially expressed in metastatic melanoma cells."Jpn. J. Cancer Res. 92:140-151(2001) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner."Genomics 89:618-629(2007) [PubMed] [Europe PMC] [Abstract]