Matrix Metalloproteinase 26 (MMP26)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.

The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.

Organism species: Homo sapiens (Human)

Proteins RPB256Hu01 Recombinant Matrix Metalloproteinase 26 (MMP26) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB256Hu01 Polyclonal Antibody to Matrix Metalloproteinase 26 (MMP26) WB; IHC; ICC; IP.
MAB256Hu22 Monoclonal Antibody to Matrix Metalloproteinase 26 (MMP26) WB; IHC; ICC; IP.
Assay Kits SEB256Hu ELISA Kit for Matrix Metalloproteinase 26 (MMP26) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Cloning of MMP-26 A novel matrilysin-like proteinase."Eur. J. Biochem. 267:3323-3329(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Matrilysin-2, a new matrix metalloproteinase expressed in human tumors and showing the minimal domain organization required for secretion, latency, and activity."Cancer Res. 60:4745-4751(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Identification and characterization of Homo sapiens endometase (matrix metalloproteinase-26) from endometrial tumor."J. Biol. Chem. 275:20540-20544(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin."Biochem. J. 356:705-718(2001) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]