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Elongin A (ELOA)

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Elo-A; TCEB3; SIII p110; TCEB3A; Transcription Elongation Factor B Polypeptide 3; Elongin 110 kDa subunit; RNA polymerase II transcription factor SIII subunit A1

Elongin A (ELOA)
CCC B255
HGNC 11620
MGI 1351315
PubMed 23122963
RGD 3827
UniProt Q14241
Wiki TCEB3

Transcription elongation factor B polypeptide 3 is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.

Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Elongin A (ELOA) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Elongin A (ELOA) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Elongin A (ELOA) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Elongin A (ELOA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Elongin A (ELOA) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB255Mu01 Recombinant Elongin A (ELOA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB255Mu01 Polyclonal Antibody to Elongin A (ELOA) WB; IHC
Assay Kits n/a CLIA Kit for Elongin A (ELOA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Elongin A (ELOA) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB255Ra01 Recombinant Elongin A (ELOA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB255Ra01 Polyclonal Antibody to Elongin A (ELOA) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Elongin A (ELOA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Elongin A (ELOA) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "A human cDNA encoding the 110-kDa A subunit of RNA polymerase II transcription factor elongin."Gene 168:277-278(1996) [PubMed] [Europe PMC] [Abstract]
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  8. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]