≡

Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1)

[Edit]

CD66f; PSb1G; PSb1-G; DHFRP2; PBG1; B1G1; PSBG1; PSGGA; PSGIIA; SP1; PS-beta-C/D; CD66 antigen-like family member F; Fetal liver non-specific cross-reactive antigen 1/2

Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1)
CCC B192
HGNC 9514
PubMed 10703955
UniProt P11464
Wiki PSG1

Pregnancy specific β1 glycoprotein (SP1) is a specific protein which is produced by syncytial cells in placental, its molecular wightis 90, 000～110, 000Daldon, 29％ of glycomolecular, 30 hours of half life. SP1 was 97. 4％ in pregnant women of 6-8 weeks, SP1 was determinated in 100％ pregnant women at late peroid, but it was not in the normal non-pregnant women and males.The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development.

Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976). PSG is a member of the immunoglobulin (Ig) superfamily .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB192Hu01 Recombinant Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB192Hu01 Polyclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) ELISA Kit Customized Service Offer
  1. "The human pregnancy-specific beta 1-glycoprotein (PS beta G) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family."Biochem. Biophys. Res. Commun. 154:130-137(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of cDNA encoding human pregnancy-specific beta 1-glycoprotein from placenta and extraplacental tissues and their comparison with carcinoembryonic antigen."DNA 7:545-555(1988) [PubMed] [Europe PMC] [Abstract]
  3. "Carcinoembryonic antigen gene family: molecular cloning of cDNA for a PS-beta-G/FL-NCA glycoprotein with a novel domain arrangement."Biochem. Biophys. Res. Commun. 161:525-535(1989) [PubMed] [Europe PMC] [Abstract]
  4. "cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver."Biochem. Biophys. Res. Commun. 163:1197-1209(1989) [PubMed] [Europe PMC] [Abstract]
  5. "Linkage of two human pregnancy-specific beta 1-glycoprotein genes: one is associated with hydatidiform mole."Proc. Natl. Acad. Sci. U.S.A. 87:5822-5826(1990) [PubMed] [Europe PMC] [Abstract]
  6. "Isolation and characterization of complementary DNAs encoding human pregnancy-specific beta 1-glycoprotein."J. Biol. Chem. 263:2049-2054(1988) [PubMed] [Europe PMC] [Abstract]
  7. "Molecular cloning and expression of cDNA for a carcinoembryonic antigen-related fetal liver glycoprotein."Proc. Natl. Acad. Sci. U.S.A. 86:3332-3336(1989) [PubMed] [Europe PMC] [Abstract]
  8. "Carcinoembryonic antigen gene family members in submandibular salivary gland: demonstration of pregnancy-specific glycoproteins by cDNA cloning."Biochem. Biophys. Res. Commun. 169:203-216(1990) [PubMed] [Europe PMC] [Abstract]
  9. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]