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Cadherin, Osteoblast (CDHOB)

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CDH11; CAD11; OB; OSF4; Cadherin 11 Type 2; OB-Cadherin

Cadherin, Osteoblast (CDHOB)
CCC B137
HGNC 1750
MGI 99217
PubMed 10029089
UniProt P55287
Wiki CDH11

Cadherin-11 is type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion.

Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.

Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB137Hu01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB137Hu01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; ICC; IHC-P; IHC-F; ELISA.
MAB137Hu22 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
MAB137Hu21 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
Assay Kits SEB137Hu ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cadherin, Osteoblast (CDHOB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cadherin, Osteoblast (CDHOB) ELISA Kit Customized Service Offer
  1. "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin."Cell Adhes. Commun. 2:15-26(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts."J. Biol. Chem. 269:12092-12098(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue."Cell Regul. 2:261-270(1991) [PubMed] [Europe PMC] [Abstract]
  6. "USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst."Cancer Res. 64:1920-1923(2004) [PubMed] [Europe PMC] [Abstract]