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Ubiquitin Protein Ligase E3A (UBE3A)

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ANCR; AS; E6-AP; EPVE6AP; HPVE6A; Papilloma Virus E6-Associated,Angelman Syndrome; Oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY-REN-54

Ubiquitin Protein Ligase E3A (UBE3A)
CCC B072
HGNC 12496
MGI 105098
PubMed 22681684
UniProt Q05086
Wiki UBE3A

Ubiquitin-protein ligase E3A (UBE3A) is an enzyme that in humans is encoded by the UBE3A gene. This enzyme is involved in targeting proteins for degradation within cells. Protein degradation is a normal process that removes damaged or unnecessary proteins and helps maintain the normal functions of cells. Ubiquitin protein ligase 3A attaches a small protein called ubiquitin to proteins that should be degraded. Cellular structures called proteasomes recognize and digest proteins tagged with ubiquitin. Both copies of the UBE3A gene are active in most of the body's tissues. In the brain, however, only the copy inherited from a person's mother (the maternal copy) is normally active. The UBE3A gene is located on the long (q) arm of chromosome 15 between positions 11 and 13, from base pair 23,133,488 to base pair 23,235,220.

 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB072Hu01 Recombinant Ubiquitin Protein Ligase E3A (UBE3A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB072Hu01 Polyclonal Antibody to Ubiquitin Protein Ligase E3A (UBE3A) WB; IHC; ICC; IP.
MAB072Hu22 Monoclonal Antibody to Ubiquitin Protein Ligase E3A (UBE3A) WB; IHC; ICC; IP.
Assay Kits SEB072Hu ELISA Kit for Ubiquitin Protein Ligase E3A (UBE3A) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Protein Ligase E3A (UBE3A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Protein Ligase E3A (UBE3A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Protein Ligase E3A (UBE3A) Polyclonal Antibody Customized Service Offer
Assay Kits SEB072Mu ELISA Kit for Ubiquitin Protein Ligase E3A (UBE3A) Enzyme-linked immunosorbent assay for Antigen Detection.
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