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Protein Tyrosine Phosphatase Receptor Type K (PTPRK)

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R-PTP-Kappa; PTPR-K; Protein-tyrosine phosphatase kappa

Protein Tyrosine Phosphatase Receptor Type K (PTPRK)
CCC B047
HGNC 9674
MGI 103310
PubMed 18276111
UniProt Q15262
Wiki PTPRK
Receptor-type tyrosine-protein phosphatase kappa isa member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB047Hu01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB047Hu01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) ELISA Kit Customized Service Offer
  1. "Association of human protein-tyrosine phosphatase kappa with members of the armadillo family."J. Biol. Chem. 271:16712-16719(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and chromosomal localization of a human gene homologous to the murine R-PTP-kappa, a receptor-type protein tyrosine phosphatase."Gene 186:77-82(1997) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis."Curr. Biol. 19:1788-1798(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Large-scale structural analysis of the classical human protein tyrosine phosphatome."Cell 136:352-363(2009) [PubMed] [Europe PMC] [Abstract]