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Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus and the locus coeruleus, although NPS-responsive neurons extend projections into many other brain areas.
NPS binds specifically to a newly de-orphaned G protein-coupled receptor, NPSR. Animal studies show that NPS suppresses anxiety and induces wakefulness and displays significant role in the extinction of conditioned fear. The non-peptide NPS receptor antagonist SHA-68 blocks the effects of NPS in animals and is anxiogenic. Several peptide derived NPS agonists and antagonists have also been developed.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA796Hu01 | Recombinant Neuropeptide S (NPS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| SPA796Hu01 | Synthetic Neuropeptide S (NPS) | Immunogen; Blocking Peptide. | |
| CPA796Hu21 | OVA Conjugated Neuropeptide S (NPS) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA796Hu01 | Polyclonal Antibody to Neuropeptide S (NPS) | WB; IHC; ICC; IP. |
| MAA796Hu22 | Monoclonal Antibody to Neuropeptide S (NPS) | WB; IHC; ICC; IP. | |
| LAA796Hu71 | Biotin-Linked Polyclonal Antibody to Neuropeptide S (NPS) | WB; IHC; ICC. | |
| Assay Kits | CEA796Hu | ELISA Kit for Neuropeptide S (NPS) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA796Mu01 | Recombinant Neuropeptide S (NPS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPA796Mu21 | OVA Conjugated Neuropeptide S (NPS) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA796Mu01 | Polyclonal Antibody to Neuropeptide S (NPS) | WB; IHC; ICC; IP. |
| Assay Kits | CEA796Mu | ELISA Kit for Neuropeptide S (NPS) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA796Ra01 | Recombinant Neuropeptide S (NPS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA796Ra01 | Polyclonal Antibody to Neuropeptide S (NPS) | WB; IHC; ICC; IP. |
| MAA796Ra21 | Monoclonal Antibody to Neuropeptide S (NPS) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA796Ra | ELISA Kit for Neuropeptide S (NPS) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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