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Membrane Protein, Palmitoylated 5 (MPP5)

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PALS1; Stardust; MAGUK P55 Subfamily Member 5

Membrane Protein, Palmitoylated 5 (MPP5)
CCC A744
HGNC 18669
MGI 1927339
PubMed 16885194
RGD 1308071
UniProt Q8N3R9
Wiki MPP5

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins.

All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like, ZO1-like, p55-like, and LIN2-like, based on their size and the presence of additional domains (Tseng et al., 2001).

MPP5 is a member of the p55-like MAGUK subfamily.The International Radiation Hybrid Mapping Consortium mapped the MPP5 gene to chromosome 14 . Kamberov et al. (2000) mapped the mouse Pals1 gene to chromosome 12.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA744Hu01 Recombinant Membrane Protein, Palmitoylated 5 (MPP5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA744Hu01 Polyclonal Antibody to Membrane Protein, Palmitoylated 5 (MPP5) WB,IHC
Assay Kits n/a CLIA Kit for Membrane Protein, Palmitoylated 5 (MPP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Protein, Palmitoylated 5 (MPP5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Membrane Protein, Palmitoylated 5 (MPP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Membrane Protein, Palmitoylated 5 (MPP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Membrane Protein, Palmitoylated 5 (MPP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Membrane Protein, Palmitoylated 5 (MPP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Protein, Palmitoylated 5 (MPP5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Membrane Protein, Palmitoylated 5 (MPP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Membrane Protein, Palmitoylated 5 (MPP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Membrane Protein, Palmitoylated 5 (MPP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Membrane Protein, Palmitoylated 5 (MPP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Protein, Palmitoylated 5 (MPP5) ELISA Kit Customized Service Offer
  1. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "MPP5 recruits MPP4 to the CRB1 complex in photoreceptors."Invest. Ophthalmol. Vis. Sci. 46:2192-2201(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina."J. Comp. Neurol. 481:31-41(2005) [PubMed] [Europe PMC] [Abstract]
  6. "A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells."Cell 125:535-548(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation."Mol. Biol. Cell 18:1744-1755(2007) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins."Proc. Natl. Acad. Sci. U.S.A. 102:6861-6866(2005) [PubMed] [Europe PMC] [Abstract]
  12. "MPP1 links the Usher protein network and the Crumbs protein complex in the retina."Hum. Mol. Genet. 16:1993-2003(2007) [PubMed] [Europe PMC] [Abstract]