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Alcohol Dehydrogenase 1 (ADH1)

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ADH1A; Alcohol Dehydrogenase 1A(Class I)Alpha Polypeptide; Alcohol dehydrogenase subunit alpha

Alcohol Dehydrogenase 1 (ADH1)
CCC A681
HGNC 249
MGI 87921
PubMed 8883381
RGD 2044
UniProt P07327
Wiki ADH1A

Alcohol dehydrogenase 1A is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism.

Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. This gene is monomorphic and predominant in fetal and infant livers, whereas the genes encoding beta and gamma subunits are polymorphic and strongly expressed in adult livers.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA681Hu01 Recombinant Alcohol Dehydrogenase 1 (ADH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA681Hu01 Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) WB; IHC
MAA681Hu22 Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) WB; IHC; ICC; IP.
Assay Kits SEA681Hu ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA681Mu01 Recombinant Alcohol Dehydrogenase 1 (ADH1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA681Mu02 Recombinant Alcohol Dehydrogenase 1 (ADH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA681Mu01 Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) WB,IHC
PAA681Mu02 Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) WB; IHC; ICC; IP.
Assay Kits SEA681Mu ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA681Ra01 Recombinant Alcohol Dehydrogenase 1 (ADH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA681Ra01 Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) WB; IHC; ICC; IP.
MAA681Ra21 Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) WB; IHC; ICC; IP.
Assay Kits SEA681Ra ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "cDNA and protein structure for the alpha subunit of human liver alcohol dehydrogenase."Biochemistry 25:2465-2470(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence."Proc. Natl. Acad. Sci. U.S.A. 83:634-638(1986) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular structure of the human alcohol dehydrogenase 1 gene."FEBS Lett. 243:57-60(1989) [PubMed] [Europe PMC] [Abstract]
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  6. "The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome."Genomics 7:152-158(1990) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors."Biochemistry 43:12555-12562(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Three-dimensional structures of the three human class I alcohol dehydrogenases."Protein Sci. 10:697-706(2001) [PubMed] [Europe PMC] [Abstract]