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Glutathione S Transferase Mu 3, Brain (GSTm3)

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GST-M3; GST5; GSTB; GSTM3-3; GTM3

Glutathione S Transferase Mu 3, Brain (GSTm3)
CCC A654
HGNC 4635
MGI 1309466
PubMed 17220350
RGD 620381
UniProt P21266
Wiki GSTM3
In brain extracts, Van Cong et al. (1984) observed a novel GST band (GST5, or GSTM3) which is probably controlled by an independent gene.
By immunoblotting, Campbell et al. (1990) identified GSTM3, a mu-class GST with an isoelectric point of 5.2. GSTM1 is prevalent in testis and found in cerebral cortex but not liver.
Campbell et al. (1990) detected GSTM3 in all 13 testes and 28 brain samples tested, including those from individuals devoid of GSTM1 because of a GSTM1 gene deletion. These authors cloned GSTM3 cDNAs from human brain and testis cDNA libraries. The predicted 225-amino acid protein shares 72% sequence similarity with GSTM1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA654Hu01 Recombinant Glutathione S Transferase Mu 3, Brain (GSTm3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA654Hu01 Polyclonal Antibody to Glutathione S Transferase Mu 3, Brain (GSTm3) WB; IHC; ICC; IP.
MAA654Hu21 Monoclonal Antibody to Glutathione S Transferase Mu 3, Brain (GSTm3) WB; IHC; ICC; IP.
Assay Kits SEA654Hu ELISA Kit for Glutathione S Transferase Mu 3, Brain (GSTm3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutathione S Transferase Mu 3, Brain (GSTm3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutathione S Transferase Mu 3, Brain (GSTm3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutathione S Transferase Mu 3, Brain (GSTm3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutathione S Transferase Mu 3, Brain (GSTm3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutathione S Transferase Mu 3, Brain (GSTm3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutathione S Transferase Mu 3, Brain (GSTm3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutathione S Transferase Mu 3, Brain (GSTm3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutathione S Transferase Mu 3, Brain (GSTm3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutathione S Transferase Mu 3, Brain (GSTm3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutathione S Transferase Mu 3, Brain (GSTm3) ELISA Kit Customized Service Offer
  1. "A distinct human testis and brain mu-class glutathione S-transferase. Molecular cloning and characterization of a form present even in individuals lacking hepatic type mu isoenzymes."J. Biol. Chem. 265:9188-9193(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Distinctive structure of the human GSTM3 gene-inverted orientation relative to the mu class glutathione transferase gene cluster."Arch. Biochem. Biophys. 361:85-93(1999) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript."Biochem. J. 294:373-380(1993) [PubMed] [Europe PMC] [Abstract]
  5. "Human Mu-class glutathione S-transferases present in liver, skeletal muscle and testicular tissue."Biochim. Biophys. Acta 1203:131-141(1993) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases."Biochemistry 38:16187-16194(1999) [PubMed] [Europe PMC] [Abstract]