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Glutathione S Transferase Omega 1 (GSTo1)

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P28; GSTTLp28; GSTw1; SPG-R; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase

Glutathione S Transferase Omega 1 (GSTo1)
CCC A623
HGNC 13312
MGI 1342273
PubMed 20106899
RGD 70952
UniProt P78417
Wiki GSTO1

Glutathione S-transferase omega-1 is an enzyme that  encodes a member of the theta class glutathione S-transferase-like (GSTTL) protein family. In mouse, the encoded protein acts as a small stress response protein, likely involved in cellular redox homeostasis.This protein has dehydroascorbate reductase activity and may function in the glutathione-ascorbate cycle as part of antioxidant metabolism.

GSTO1 has an N-terminal thioredoxin-like domain consisting of a central 4-stranded beta sheet flanked on one side by 2 alpha helices and on the other by a 3-10 helix. The C terminus is composed of 7 alpha helices and makes several H bonds with the N-terminal domain. GSTO1 forms a dimer and adopts the typical GST tertiary structure.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA623Hu01 Recombinant Glutathione S Transferase Omega 1 (GSTo1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA623Hu01 Polyclonal Antibody to Glutathione S Transferase Omega 1 (GSTo1) WB; IHC; ICC; IP.
MAA623Hu22 Monoclonal Antibody to Glutathione S Transferase Omega 1 (GSTo1) WB; IHC; ICC; IP.
Assay Kits SEA623Hu ELISA Kit for Glutathione S Transferase Omega 1 (GSTo1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA623Mu01 Recombinant Glutathione S Transferase Omega 1 (GSTo1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA623Mu02 Recombinant Glutathione S Transferase Omega 1 (GSTo1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA623Mu01 Polyclonal Antibody to Glutathione S Transferase Omega 1 (GSTo1) WB; IHC; ICC; IP.
PAA623Mu02 Polyclonal Antibody to Glutathione S Transferase Omega 1 (GSTo1) WB; IHC; ICC; IP.
Assay Kits SEA623Mu ELISA Kit for Glutathione S Transferase Omega 1 (GSTo1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutathione S Transferase Omega 1 (GSTo1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutathione S Transferase Omega 1 (GSTo1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutathione S Transferase Omega 1 (GSTo1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutathione S Transferase Omega 1 (GSTo1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutathione S Transferase Omega 1 (GSTo1) ELISA Kit Customized Service Offer
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  2. "Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans."Environ. Health Perspect. 111:1421-1427(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping."Electrophoresis 21:3785-3796(2000) [PubMed] [Europe PMC] [Abstract]
  7. "Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily."Chem. Res. Toxicol. 14:1051-1057(2001) [PubMed] [Europe PMC] [Abstract]
  8. "Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones."Chem. Res. Toxicol. 20:149-154(2007) [PubMed] [Europe PMC] [Abstract]
  9. "S-(4-Nitrophenacyl)glutathione is a specific substrate for glutathione transferase omega 1-1."Anal. Biochem. 374:25-30(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1."J. Biol. Chem. 286:4271-4279(2011) [PubMed] [Europe PMC] [Abstract]
  15. "Characterization of the human Omega class glutathione transferase genes and associated polymorphisms."Pharmacogenetics 13:131-144(2003) [PubMed] [Europe PMC] [Abstract]