Immunoglobulin E (IgE)

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IGHE; Immunoglobulin Heavy Constant Epsilon; Ig epsilon chain C region

Immunoglobulin E (IgE)

Immunoglobulin E (IgE) is a class of antibody produced in the lungs, skin, and mucous membranes that has only been found in mammals. It plays an important role in allergy, and is especially associated with type 1 hypersensitivity. IgE has also been implicated in immune system responses to most parasitic worms like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica, and may be important during immune defense against certain protozoan parasites such as Plasmodium falciparum. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA545Hu01 Recombinant Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
NPA545Hu01 Native Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA545Hu01 Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
MAA545Hu22 Monoclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
LAA545Hu71 Biotin-Linked Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC.
Assay Kits SEA545Hu ELISA Kit for Immunoglobulin E (IgE) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NPA545Mu01 Native Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
RPA545Mu01 Recombinant Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
RPA545Mu02 Recombinant Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA545Mu01 Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
LAA545Mu71 Biotin-Linked Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC.
PAA545Mu02 Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
Assay Kits SEA545Mu ELISA Kit for Immunoglobulin E (IgE) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA545Mu CLIA Kit for Immunoglobulin E (IgE) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NPA545Ra01 Native Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
RPA545Ra01 Recombinant Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA545Ra01 Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
MAA545Ra21 Monoclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
Assay Kits SEA545Ra ELISA Kit for Immunoglobulin E (IgE) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Immunoglobulin E (IgE) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Immunoglobulin E (IgE) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Immunoglobulin E (IgE) Polyclonal Antibody Customized Service Offer
Assay Kits SEA545Rb ELISA Kit for Immunoglobulin E (IgE) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NPA545Po01 Native Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
RPA545Po01 Recombinant Immunoglobulin E (IgE) Positive Control; Immunogen; SDS-PAGE; WB.
CPA545Po21 OVA Conjugated Immunoglobulin E (IgE) Immunogen; SDS-PAGE; WB.
Antibodies PAA545Po01 Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
MAA545Po21 Monoclonal Antibody to Immunoglobulin E (IgE) IHC; ICC; IP.
PAA545Po08 Polyclonal Antibody to Immunoglobulin E (IgE) WB; IHC; ICC; IP.
Assay Kits SEA545Po ELISA Kit for Immunoglobulin E (IgE) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Duplication and deletion in the human immunoglobulin epsilon genes."Cell 29:691-699(1982) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes."EMBO J. 1:655-660(1982) [PubMed] [Europe PMC] [Abstract]
  3. "Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns."EMBO J. 1:1539-1544(1982) [PubMed] [Europe PMC] [Abstract]
  4. "Molecular cloning and nucleotide sequencing of human immunoglobulin epsilon chain cDNA."Nucleic Acids Res. 11:719-726(1983) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  6. (In) Bach M.K. (eds.);Immediate hypersensitivity: modern concepts and developments, pp.1-36, Marcel Dekker, New York (1978)
  7. "Cloning and sequence determination of the gene for the human immunoglobulin epsilon chain expressed in a myeloma cell line."Proc. Natl. Acad. Sci. U.S.A. 79:6661-6665(1982) [PubMed] [Europe PMC] [Abstract]
  8. "A model of the Fc of immunoglobulin E."Mol. Immunol. 23:1063-1075(1986) [PubMed] [Europe PMC] [Abstract]