Cholecystokinin 4, Tetrapeptide (CCK4)

[Edit]

Trp-Met-Asp-Phe-NH2

Cholecystokinin 4, Tetrapeptide (CCK4)

CCK-4 is a peptide fragment derived from the larger peptide hormone cholecystokinin. Unlike cholecystokin which has a variety of roles in the gastrointenstinal system as well as central nervous system effects, CCK-4 acts primarily in the brain as an anxiogenic, although it does retain some GI effects, but not as much as CCK-8 or the full length polypeptide CCK-58. CCK-4 reliably causes severe anxiety symptoms when administered to humans in a dose of as little as 50μg,and is commonly used in scientific research to induce panic attacks for the purpose of testing new anxiolytic drugs. Since it is a peptide, CCK-4 must be administered by injection, and is rapidly broken down once inside the body so has only a short duration of action, although numerous synthetic analogues with modified properties are known.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA378Hu01 Recombinant Cholecystokinin 4, Tetrapeptide (CCK4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cholecystokinin 4, Tetrapeptide (CCK4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cholecystokinin 4, Tetrapeptide (CCK4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cholecystokinin 4, Tetrapeptide (CCK4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cholecystokinin 4, Tetrapeptide (CCK4) ELISA Kit Customized Service Offer