Interferon Gamma Induced Protein 10kDa (IP10)

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CXCL10; C7; IFI10; INP10; SCYB10; Crg2; GIP10; Mob1; Chemokine C-X-C Motif Ligand 10; Small Inducible Cytokine Subfamily B(Cys-X-Cys)Member 10

Interferon Gamma Induced Protein 10kDa (IP10)

Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein (γ-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts.

CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA371Hu01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
APA371Hu01 Active Interferon Gamma Induced Protein 10kDa (IP10) Cell culture; Activity Assays.
Antibodies PAA371Hu01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
MAA371Hu22 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
LAA371Hu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC.
LAA371Hu81 FITC-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
Assay Kits SEA371Hu ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA371Mu01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
RPA371Mu02 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA371Mu01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
LAA371Mu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC.
LAA371Mu81 FITC-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IF.
PAA371Mu02 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
Assay Kits SEA371Mu ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA371Ra01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA371Ra01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
MAA371Ra21 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
Assay Kits SEA371Ra ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Hamster (Chinese hamster)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA371Ha01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA371Ca01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA371Ca01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
LAA371Ca71 Biotin-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC.
MAA371Ca21 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
Assay Kits SEA371Ca ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA371Bo01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA371Bo01 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
MAA371Bo21 Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) WB; IHC; ICC; IP.
Assay Kits SEA371Bo ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins."Nature 315:672-676(1985) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of a novel granulocyte chemotactic protein (GCP-2) from human tumor cells. In vitro and in vivo comparison with natural forms of GRO, IP-10, and IL-8."J. Immunol. 150:1000-1010(1993) [PubMed] [Europe PMC] [Abstract]
  4. "Human IP-9: a keratinocyte derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)."J. Invest. Dermatol. 112:716-722(1999) [PubMed] [Europe PMC] [Abstract]
  5. "Processing of natural and recombinant CXCR3-targeting chemokines and implications for biological activity."Eur. J. Biochem. 268:4992-4999(2001) [PubMed] [Europe PMC] [Abstract]
  6. "Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation."Blood 112:2648-2656(2008) [PubMed] [Europe PMC] [Abstract]
  7. "The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions."Biochemistry 41:10418-10425(2002) [PubMed] [Europe PMC] [Abstract]