Galectin 7 (GAL7)
[Edit]LGALS7; PIG1; TP53I1; HKL-14; Lectin Galactoside-Binding Soluble 7; p53-induced gene 1 protein
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Galectin-7, a member of this family, contributes to different events associated with the differentiation and development of pluristratified epithelia. It is also associated with epithelial cell migration, which plays a crucial role in the re-epithelialization process of corneal or epidermal wounds.
In addition, recent evidence indicates that galectin-7, designated as the product of the p53-induced gene 1 (PIG1), is a regulator of apoptosis through JNK activation and mitochondrial cytochrome c release. Defects in apoptosis constitute one of the major hallmarks of human cancers, and galectin-7 can act as either a positive or a negative regulatory factor in tumour development, depending on the histological type of the tumour.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA307Hu01 | Recombinant Galectin 7 (GAL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA307Hu01 | Active Galectin 7 (GAL7) | Cell culture; Activity Assays. | |
| Antibodies | PAA307Hu01 | Polyclonal Antibody to Galectin 7 (GAL7) | WB |
| MAA307Hu22 | Monoclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC; IP. | |
| LAA307Hu71 | Biotin-Linked Polyclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC. | |
| MAA307Hu21 | Monoclonal Antibody to Galectin 7 (GAL7) | WB | |
| LAA307Hu72 | Biotin-Linked Monoclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC. | |
| MAA307Hu23 | Monoclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC; IP. | |
| MAA307Hu24 | Monoclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC; IP. | |
| MAA307Hu25 | Monoclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA307Hu | ELISA Kit for Galectin 7 (GAL7) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA307Mu01 | Recombinant Galectin 7 (GAL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA307Mu01 | Active Galectin 7 (GAL7) | Cell culture; Activity Assays. | |
| Antibodies | PAA307Mu01 | Polyclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Galectin 7 (GAL7) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Galectin 7 (GAL7) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA307Ra01 | Recombinant Galectin 7 (GAL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA307Ra01 | Active Galectin 7 (GAL7) | Cell culture; Activity Assays. | |
| Antibodies | PAA307Ra01 | Polyclonal Antibody to Galectin 7 (GAL7) | WB; IHC |
| LAA307Ra71 | Biotin-Linked Polyclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC. | |
| LAA307Ra81 | FITC-Linked Polyclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC; IF. | |
| MAA307Ra21 | Monoclonal Antibody to Galectin 7 (GAL7) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA307Ra | ELISA Kit for Galectin 7 (GAL7) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Cloning, expression, and chromosome mapping of human galectin-7."J. Biol. Chem. 270:5823-5829(1995) [PubMed] [Europe PMC] [Abstract]
- "Galectin-7, a human 14-kDa S-lectin, specifically expressed in keratinocytes and sensitive to retinoic acid."Dev. Biol. 168:259-271(1995) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release."J. Biol. Chem. 277:3487-3497(2002) [PubMed] [Europe PMC] [Abstract]
- "Structural basis for the recognition of carbohydrates by human galectin-7."Biochemistry 37:13930-13940(1998) [PubMed] [Europe PMC] [Abstract]