Maltase Glucoamylase, Intestinal (MGA)

[Edit]

MGAM; Glucan 1,4-Alpha-Glucosidase

Maltase Glucoamylase, Intestinal (MGA)

Maltase-glucoamylase (MGA) is a brush border membrane enzyme that plays a role in the final steps of small intestinal digestion of linear regions of starch to glucose. Brush border sucrase-isomaltase (SI) serves a complementary function through digestion of branched starch linkages. Brush-border maltase-glucoamylase (MGA) activity serves as the final step of small intestinal digestion of linear regions of dietary starch to glucose.

Maltase-glucoamylase is synthesized as a single-chain polypeptide precursor, acquires N- and O-linked carbohydrates, and does not undergo intracellular or extracellular proteolytic cleavage. Maltase is an enzyme produced by the cells lining the small intestine that breaks down the disaccharide maltose. It comes under the enzyme category carbohydrase.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA253Hu01 Recombinant Maltase Glucoamylase, Intestinal (MGA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA253Hu01 Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
MAA253Hu22 Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) WB; IHC; ICC; IP.
Assay Kits SEA253Hu ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Maltase Glucoamylase, Intestinal (MGA) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Maltase Glucoamylase, Intestinal (MGA) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Maltase Glucoamylase, Intestinal (MGA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Maltase Glucoamylase, Intestinal (MGA) ELISA Kit Customized Service Offer
  1. "Human small intestinal maltase-glucoamylase cDNA cloning. Homology to sucrase-isomaltase."J. Biol. Chem. 273:3076-3081(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase."J. Biol. Chem. 263:19709-19717(1988) [PubMed] [Europe PMC] [Abstract]
  5. "Tyrosine sulfation, a post-translational modification of microvillar enzymes in the small intestinal enterocyte."EMBO J. 6:2891-2896(1987) [PubMed] [Europe PMC] [Abstract]
  6. "Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity."J. Mol. Biol. 375:782-792(2008) [PubMed] [Europe PMC] [Abstract]