Complement 1 Inhibitor (C1INH)

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SERPING1; C1IN; C1-INH; C1NH; HAE1; HAE2; Serpin Peptidase Inhibitor Clade G Member 1; Angioedema Hereditary; C1 Inhibitor; C1 Esterase Inhibitor

Complement 1 Inhibitor (C1INH)

C1-INH is a critically important protein that controls activation of multiple plasma mediator pathways. This protein, a member of the serine protease inhibitor (serpin) group, originally was described as an inhibitor of C1. It binds stoichiometrically to the active sites on both C1r and C1s to form a complex C1-INH-C1r-C1s-C1-INH and thus inhibits activated C1. In addition, C1-INH has been reported to remove the intact C1qrs complex from an activating surface and to inhibit autoactivation of C1. C1-INH is a known inhibitor of kinin generating (kallikrein), fibrinolytic (plasmin), and contact activation (intrinsic) pathway of the coagulation cascade. Recently, it has been shown to be an inhibitor of the mannan-binding lectin pathway of complement activation, inhibiting mannan-binding lectin-associated serine proteases (MASPs) in that pathway.

 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA235Hu01 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
RPA235Hu02 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA235Hu01 Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
MAA235Hu22 Monoclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
LAA235Hu71 Biotin-Linked Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC.
LAA235Hu81 FITC-Linked Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IF.
MAA235Hu21 Monoclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
LAA235Hu72 Biotin-Linked Monoclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC.
Assay Kits SEA235Hu ELISA Kit for Complement 1 Inhibitor (C1INH) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA235Hu CLIA Kit for Complement 1 Inhibitor (C1INH) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA235Mu01 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
RPA235Mu02 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
RPA235Mu03 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
RPA235Mu04 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA235Mu01 Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
PAA235Mu03 Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
PAA235Mu02 Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
LAA235Mu71 Biotin-Linked Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC.
LAA235Mu81 FITC-Linked Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IF.
Assay Kits SEA235Mu ELISA Kit for Complement 1 Inhibitor (C1INH) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA235Ra01 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
RPA235Ra02 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA235Ra01 Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
PAA235Ra02 Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
LAA235Ra71 Biotin-Linked Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC.
LAA235Ra81 FITC-Linked Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IF.
Assay Kits SEA235Ra ELISA Kit for Complement 1 Inhibitor (C1INH) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA235Rb01 Recombinant Complement 1 Inhibitor (C1INH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA235Rb51 Polyclonal Antibody to Complement 1 Inhibitor (C1INH) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Complement 1 Inhibitor (C1INH) CLIA Kit Customized Service Offer
n/a ELISA Kit for Complement 1 Inhibitor (C1INH) ELISA Kit Customized Service Offer
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