Interferon Alpha 4 (IFNa4)
[Edit]INFA4; Interferon Alpha-4B; Interferon Alpha-76; Interferon Alpha-M1
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The IFNA4 gene was positioned in the cluster of interferon genes on 9p22 by deletion mapping.Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens—such as viruses, bacteria, or parasites—or tumor cells. IFNs belong to the large class of glycoproteins known as cytokines. Although they are named after their ability to "interfere" with viral replication within host cells, IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA175Hu01 | Recombinant Interferon Alpha 4 (IFNa4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA175Hu01 | Active Interferon Alpha 4 (IFNa4) | Cell culture; Activity Assays. | |
| Antibodies | PAA175Hu01 | Polyclonal Antibody to Interferon Alpha 4 (IFNa4) | WB |
| MAA175Hu22 | Monoclonal Antibody to Interferon Alpha 4 (IFNa4) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA175Hu | ELISA Kit for Interferon Alpha 4 (IFNa4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA175Hu | CLIA Kit for Interferon Alpha 4 (IFNa4) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA175Mu01 | Recombinant Interferon Alpha 4 (IFNa4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA175Mu61 | Eukaryotic Interferon Alpha 4 (IFNa4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA175Mu61 | Active Interferon Alpha 4 (IFNa4) | Cell culture; Activity Assays. | |
| Antibodies | PAA175Mu01 | Polyclonal Antibody to Interferon Alpha 4 (IFNa4) | WB; IHC; ICC; IP. |
| LAA175Mu71 | Biotin-Linked Polyclonal Antibody to Interferon Alpha 4 (IFNa4) | WB; IHC; ICC. | |
| Assay Kits | SEA175Mu | ELISA Kit for Interferon Alpha 4 (IFNa4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA175Ra01 | Recombinant Interferon Alpha 4 (IFNa4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA175Ra01 | Polyclonal Antibody to Interferon Alpha 4 (IFNa4) | WB,IHC |
| Assay Kits | n/a | CLIA Kit for Interferon Alpha 4 (IFNa4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interferon Alpha 4 (IFNa4) | ELISA Kit Customized Service Offer |
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- "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes."Biochem. J. 329:295-302(1998) [PubMed] [Europe PMC] [Abstract]
- "Both variant forms of interferon-alpha4 gene (IFNA4a and IFNA4b) are present in the human population."J. Interferon Cytokine Res. 17:559-566(1997) [PubMed] [Europe PMC] [Abstract]