Alpha-Fetoprotein (aFP)

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A-FP; FETA; HPAFP; Alpha-Fetoglobulin; Alpha-1-fetoprotein

Alpha-Fetoprotein (aFP)

AFP) is a glycoprotein with a molecular weight of between 65,000 and 70,000 daltons including 4% of carbohydrate . During fetal development, AFP maintains high levels in the serum and drops to very low levels throughout the remainder of life.

AFP is elevated in the malignant diseases of hepatocellular, testicular nonseminomatous origin, and occasionally of other entodermal origin. AFP may be slightly elevated or persisted in the patients with large hepatic metastases or viral hepatitis. AFP measurement is widely accepted as tumor marker and for monitoring the therapeutic effectiveness of hepatocellular cancer and nonseminomatous testicular cancer .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Hu01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA153Hu02 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Hu01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
MAA153Hu22 Monoclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
LAA153Hu81 FITC-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IF.
LAA153Hu71 Biotin-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC.
PAA153Hu02 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Hu ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA153Hu CLIA Kit for Alpha-Fetoprotein (aFP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Mu01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA153Mu02 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Mu01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
LAA153Mu71 Biotin-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC.
LAA153Mu81 FITC-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IF.
PAA153Mu02 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Mu ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Ra01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Ra01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
LAA153Ra81 FITC-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IF.
LAA153Ra71 Biotin-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC.
MAA153Ra21 Monoclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Ra ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Si01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Si01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
MAA153Si21 Monoclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Si ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Ca01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Ca01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
LAA153Ca71 Biotin-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC.
MAA153Ca21 Monoclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Ca ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Po01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA153Po02 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA153Po03 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Po01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
PAA153Po02 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
LAA153Po81 FITC-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IF.
LAA153Po71 Biotin-Linked Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC.
PAA153Po03 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Po ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Bo01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Bo01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
MAA153Bo21 Monoclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Bo ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Eq01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Eq01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
MAA153Eq21 Monoclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits SEA153Eq ELISA Kit for Alpha-Fetoprotein (aFP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA153Ga01 Recombinant Alpha-Fetoprotein (aFP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA153Ga01 Polyclonal Antibody to Alpha-Fetoprotein (aFP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Alpha-Fetoprotein (aFP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alpha-Fetoprotein (aFP) ELISA Kit Customized Service Offer
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  2. "Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene."Biochemistry 26:1332-1343(1987) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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  6. "A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP)."Hum. Mol. Genet. 2:379-384(1993) [PubMed] [Europe PMC] [Abstract]
  7. , Submitted (MAR-2007) to UniProtKB
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  9. "Human alpha-fetoprotein primary structure: a mass spectrometric study."Biochemistry 30:5061-5066(1991) [PubMed] [Europe PMC] [Abstract]
  10. "Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis."Biochim. Biophys. Acta 493:418-428(1977) [PubMed] [Europe PMC] [Abstract]
  11. "Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma."Cancer Res. 37:3663-3667(1977) [PubMed] [Europe PMC] [Abstract]
  12. "Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury."Johns Hopkins Med. J. Suppl. 3:249-255(1974) [PubMed] [Europe PMC] [Abstract]
  13. "Copper(II)-binding ability of human alpha-fetoprotein."Cancer Res. 38:3483-3486(1978) [PubMed] [Europe PMC] [Abstract]
  14. "Alpha-fetoprotein as a carrier protein in plasma and its bilirubin-binding ability."Cancer Res. 39:3571-3574(1979) [PubMed] [Europe PMC] [Abstract]
  15. "Tyrosine sulfation of proteins from the human hepatoma cell line HepG2."Proc. Natl. Acad. Sci. U.S.A. 82:7160-7164(1985) [PubMed] [Europe PMC] [Abstract]
  16. "Congenital deficiency of alpha feto-protein."Eur. J. Hum. Genet. 12:871-874(2004) [PubMed] [Europe PMC] [Abstract]
  17. "A new mutation in the AFP gene responsible for a total absence of alpha feto-protein on second trimester maternal serum screening for Down syndrome."Eur. J. Hum. Genet. 17:387-390(2009) [PubMed] [Europe PMC] [Abstract]
  18. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]