Vascular Endothelial Growth Factor B (VEGFB)

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VEGF-B; VEGFL; VRF; VEGF-Related Factor

Vascular Endothelial Growth Factor B (VEGFB)

Vascular endothelial growth factor B is a growth factor that belongs to the vascular endothelial growth factor family of which VEGF-A is the best known member. In contrast to VEGF-A, VEGF-B plays a less pronounced role in the vascular system: whereas VEGF-A is important for the formation of blood vessels, such as during development or in pathological conditions, VEGF-B seems only to play in role in the maintenance of newly formed blood vessels during pathological conditions. VEGF-B plays also an important role on several types of neurons. It is important for the protection of neurons in the retina and the cerebral cortex during stroke  and of motoneurons during motor neuron diseases such as amyotrophic lateral sclerosis.VEGF-B exerts its effects via the FLT1 receptor.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA144Hu01 Recombinant Vascular Endothelial Growth Factor B (VEGFB) Positive Control; Immunogen; SDS-PAGE; WB.
APA144Hu01 Active Vascular Endothelial Growth Factor B (VEGFB) Cell culture; Activity Assays.
Antibodies PAA144Hu01 Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IP.
MAA144Hu22 Monoclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IP.
LAA144Hu82 FITC-Linked Monoclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IF.
LAA144Hu72 Biotin-Linked Monoclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC.
LAA144Hu71 Biotin-Linked Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC.
LAA144Hu81 FITC-Linked Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IF.
Assay Kits SEA144Hu ELISA Kit for Vascular Endothelial Growth Factor B (VEGFB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA144Mu01 Recombinant Vascular Endothelial Growth Factor B (VEGFB) Positive Control; Immunogen; SDS-PAGE; WB.
RPA144Mu02 Recombinant Vascular Endothelial Growth Factor B (VEGFB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA144Mu01 Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IP.
PAA144Mu02 Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IP.
Assay Kits SEA144Mu ELISA Kit for Vascular Endothelial Growth Factor B (VEGFB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA144Ra01 Recombinant Vascular Endothelial Growth Factor B (VEGFB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA144Ra01 Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Vascular Endothelial Growth Factor B (VEGFB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vascular Endothelial Growth Factor B (VEGFB) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA144Bo01 Recombinant Vascular Endothelial Growth Factor B (VEGFB) Positive Control; Immunogen; SDS-PAGE; WB.
RPA144Bo02 Recombinant Vascular Endothelial Growth Factor B (VEGFB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA144Bo01 Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Vascular Endothelial Growth Factor B (VEGFB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vascular Endothelial Growth Factor B (VEGFB) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of a novel human gene related to vascular endothelial growth factor."Genome Res. 6:124-131(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform."J. Biol. Chem. 271:19310-19317(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Vascular endothelial growth factor B, a novel growth factor for endothelial cells."Proc. Natl. Acad. Sci. U.S.A. 93:2576-2581(1996) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Crystal structure of human vascular endothelial growth factor-B: identification of amino acids important for receptor binding."J. Mol. Biol. 359:76-85(2006) [PubMed] [Europe PMC] [Abstract]