Interleukin 1 Receptor Type I (IL1R1)

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CD121a; CD121-A; IL1-R1; IL1R; IL1RA; P80; CD121 Antigen-Like Family Member A; Interleukin-1 Receptor Alpha

Interleukin 1 Receptor Type I (IL1R1)

Interleukin 1 Receptor Type I is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Both human IL1R gene and  mouse gene containing a single membrane-spanning segment, a large cytoplasmic region, and an extracellular, IL1-binding portion composed of 3 immunoglobulin-like domains.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA066Hu01 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA066Hu03 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA066Hu02 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
APA066Hu01 Active Interleukin 1 Receptor Type I (IL1R1) Cell culture; Activity Assays.
Antibodies PAA066Hu01 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; ICC; IHC-P; IHC-F; ELISA.
MAA066Hu22 Monoclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC; IP.
PAA066Hu02 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC; IP.
PAA066Hu03 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; ICC; IHC-P; IHC-F; ELISA.
LAA066Hu71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC.
Assay Kits SEA066Hu ELISA Kit for Interleukin 1 Receptor Type I (IL1R1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA066Mu01 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA066Mu02 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA066Mu01 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC; IP.
PAA066Mu02 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC; IP.
Assay Kits SEA066Mu ELISA Kit for Interleukin 1 Receptor Type I (IL1R1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA066Ra01 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA066Ra03 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA066Ra02 Recombinant Interleukin 1 Receptor Type I (IL1R1) Positive Control; Immunogen; SDS-PAGE; WB.
APA066Ra01 Active Interleukin 1 Receptor Type I (IL1R1) Cell culture; Activity Assays.
APA066Ra02 Active Interleukin 1 Receptor Type I (IL1R1) Cell culture; Activity Assays.
APA066Ra03 Active Interleukin 1 Receptor Type I (IL1R1) Cell culture; Activity Assays.
Antibodies PAA066Ra01 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC; IP.
PAA066Ra03 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC; IP.
PAA066Ra02 Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC; IP.
LAA066Ra71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Receptor Type I (IL1R1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Interleukin 1 Receptor Type I (IL1R1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 1 Receptor Type I (IL1R1) ELISA Kit Customized Service Offer
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  12. "X-ray crystal structure of a small antagonist peptide bound to interleukin-1 receptor type 1."J. Biol. Chem. 275:36927-36933(2000) [PubMed] [Europe PMC] [Abstract]