Fibroblast Growth Factor 9 (FGF9)

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GAF; HBFG9; Glia-Activating Factor; Heparin-Binding Growth Factor 9

Fibroblast Growth Factor 9 (FGF9)

Fibroblast growth factor 9(FGF9) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA036Hu01 Recombinant Fibroblast Growth Factor 9 (FGF9) Positive Control; Immunogen; SDS-PAGE; WB.
APA036Hu01 Active Fibroblast Growth Factor 9 (FGF9) Cell culture; Activity Assays.
Antibodies PAA036Hu01 Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
MAA036Hu22 Monoclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
LAA036Hu71 Biotin-Linked Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC.
Assay Kits SEA036Hu ELISA Kit for Fibroblast Growth Factor 9 (FGF9) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA036Hu CLIA Kit for Fibroblast Growth Factor 9 (FGF9) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA036Mu01 Recombinant Fibroblast Growth Factor 9 (FGF9) Positive Control; Immunogen; SDS-PAGE; WB.
RPA036Mu02 Recombinant Fibroblast Growth Factor 9 (FGF9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA036Mu01 Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
PAA036Mu02 Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
Assay Kits SEA036Mu ELISA Kit for Fibroblast Growth Factor 9 (FGF9) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA036Mu CLIA Kit for Fibroblast Growth Factor 9 (FGF9) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA036Ra01 Recombinant Fibroblast Growth Factor 9 (FGF9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA036Ra01 Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
MAA036Ra21 Monoclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
Assay Kits SEA036Ra ELISA Kit for Fibroblast Growth Factor 9 (FGF9) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA036Ra CLIA Kit for Fibroblast Growth Factor 9 (FGF9) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA036Po01 Recombinant Fibroblast Growth Factor 9 (FGF9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA036Po01 Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Fibroblast Growth Factor 9 (FGF9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibroblast Growth Factor 9 (FGF9) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA036Bo01 Recombinant Fibroblast Growth Factor 9 (FGF9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAA036Bo21 Monoclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
PAA036Bo01 Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
Assay Kits SEA036Bo ELISA Kit for Fibroblast Growth Factor 9 (FGF9) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA036Bo CLIA Kit for Fibroblast Growth Factor 9 (FGF9) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA036Ga01 Recombinant Fibroblast Growth Factor 9 (FGF9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA036Ga01 Polyclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
MAA036Ga21 Monoclonal Antibody to Fibroblast Growth Factor 9 (FGF9) WB; IHC; ICC; IP.
Assay Kits SEA036Ga ELISA Kit for Fibroblast Growth Factor 9 (FGF9) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA036Ga CLIA Kit for Fibroblast Growth Factor 9 (FGF9) Chemiluminescent immunoassay for Antigen Detection.
  1. "Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property."Mol. Cell. Biol. 13:4251-4259(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Novel secretory heparin-binding factors from human glioma cells (glia-activating factors) involved in glial cell growth. Purification and biological properties."J. Biol. Chem. 268:2857-2864(1993) [PubMed] [Europe PMC] [Abstract]
  6. "Receptor specificity of the fibroblast growth factor family."J. Biol. Chem. 271:15292-15297(1996) [PubMed] [Europe PMC] [Abstract]
  7. "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family."J. Biol. Chem. 281:15694-15700(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Fibroblast growth factor signalling: from development to cancer."Nat. Rev. Cancer 10:116-129(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces."Acta Crystallogr. D 57:378-384(2001) [PubMed] [Europe PMC] [Abstract]
  10. "Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition."J. Biol. Chem. 276:4322-4329(2001) [PubMed] [Europe PMC] [Abstract]
  11. "Multiple synostoses syndrome is due to a missense mutation in exon 2 of FGF9 gene."Am. J. Hum. Genet. 85:53-63(2009) [PubMed] [Europe PMC] [Abstract]