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New findings in periodontitis research
Periodontitis is a chronic inflammatory disease with an incidence of over 40% worldwide and has become one of the most common, challenging, and rapidly expanding oral diseases in recent years. It has been considered the main cause of tooth loss and is also connected with several system diseases, such as atherosclerosis and diabetes. Currently, the main strategy for treating periodontitis is to prevent disease progression, including mechanical debridement, antibiotics, anti-inflammatory drugs, and surgical techniques. However, the reconstruction of the periodontal tissue structure is hard to realize since the local infection and inflammation are difficult to eliminate. Recently, a numbe......
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New progress in glaucoma research
The glaucomas are a group of optic neuropathies characterized by progressive degeneration of retinal ganglion cells. Glaucoma affects more than 70 million people worldwide, making it the leading cause of irreversible blindness in the world. Glaucoma can remain asymptomatic until it is severe, resulting in a high likelihood that the number of affected individuals is much higher than the number known to have it.Glaucomas can be classified into 2 broad categories: open-angle glaucoma and angle-closure glaucoma. Both open-angle and angle-closure glaucoma can be primary diseases. Secondary glaucoma can result from trauma, certain medications such as corticosteroids, inflammation, tumor, or ......
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New findings in ovarian cancer
Ovarian cancer(OC)is one of the most common gynaecological malignancies. Approximately 90% of primary malignant ovarian tumors are epithelial (carcinomas). The classification of ovarian epithelial tumors currently used by pathologists is based entirely on tumor cell morphology. The four major types of epithelial tumors: serous, endometrioid, clear cell, and mucinous. Often known as the silent killer, OC is frequently not diagnosed until it is at an advanced stage because of its generally vague symptoms, making it hard to treat on a curative basis. Whilst the survival of patients with advanced OC has increased over the last two decades through better surgery and morechemotherapy options......
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Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice
On July 20, 2023,Jun Yu, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, China, and his team published a paper titled “Carnobacterium maltaromaticumboosts intestinal vitamin D production to suppress colorectal cancer in female mice” in Cancer Cell. They showed that Carnobacterium maltaromaticumcolonizes the gut in an estrogen-dependent manner and acts along with other microbes to augment the intestinal vitamin D production to activate the host vitamin D receptor for suppressing colorectal cancer.The kit [ELISA Kit for 7-Dehydrocholesterol (7-DHC), CED057Ge] of Cloud-Clone brand waschosed in this article, we are so proud for supporting the reaserchers......
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Research progress of irritable bowel syndrome
Irritable bowel syndrome (IBS) is a common medical condition characterized by chronic, recurrent, abdominal pain and discomfort, and altered bowel habits that occur in the absence of other organic gastrointestinal (GI) disease. IBS generates a significant health care burden and can severely impair quality of life.Altered gastrointestinal motility, visceral hypersensitivity, post infectious reactivity, brain-gut interactions, alteration in fecal micro flora, bacterial overgrowth, food sensitivity, carbohydrate malabsorption, and intestinal inflammation all have been implicated in the pathogenesis of IBS. A better understanding of the pathogenesis of IBS may help to develop new treatment......
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Pulmonary endothelium-targeted nanoassembly of indomethacin and superoxide dismutase relieves lung inflammation
On May 26, 2023,Wei He, Shanghai Skin Disease Hospital, Tongji University School of Medicine, China, and his team published a paper titled “Pulmonary endothelium-targeted nanoassembly of indomethacin and superoxide dismutase relieves lung inflammation” in Acta Pharmaceutica Sinica B. They developed the codelivery system based on rod-like pure crystals, which could well target the pulmonary endothelium and effectively alleviate lung inflammation.The kits[CLIA Kit for Tumor Necrosis Factor Alpha (TNFa), SCA133Mu; ELISA Kit for Interleukin 6 (IL6), SEA079Mu] of Cloud-Clone brand werechosed in this article, we are so proud for supporting the reaserchers.Lung inflammation is an essentia......