Cloud-Clone Clinical Diagnostic Reagents and Raw Materials #CD45 Detection Reagent #Flow Antibody

CD45 is expressed on all white blood cells and is called the leukocyte common antigen. CD45 is composed of a class of transmembrane proteins with similar structure and large molecular weight. Its cytoplasmic region acts as a protein tyrosine phosphatase, which can dephosphorylate and activate tyrosine on the substrate and play an important role in cell information transmission. As a key molecule of signal transduction on the cell membrane, CD45 plays an important role in development, maturation, function regulation and signal transmission of lymphocytes. In addition, according to the different types of CD45 molecule expressed by T cells, human T cells can be divided into CD45RA+ naive T cells and CD45RO+ memory T cells, which play different roles in the body's immune response. Therefore, CD45 detection can provide a certain basis for the clinical diagnosis and treatment of immune diseases.