Recombinant Connective Tissue Growth Factor (CTGF)
CCN2; HCS24; IGFBP8; NOV2; Insulin-Like Growth Factor-Binding Protein 8; Hypertrophic Chondrocyte-Specific Protein 24; CCN Family Member 2
- Product No.RPA010Po01
- Organism SpeciesSus scrofa; Porcine (Pig) Same name, Different species.
- SourceProkaryotic expression
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationSecreted, Extracellular matrix
- Predicted Molecular Mass26.7kDa
- Accurate Molecular Mass30kDa(Analysis of differences refer to the manual)
- Residues & TagsAla101~Pro330 with N-terminal His Tag
- Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
- Traits Freeze-dried powder
- Purity> 97%
- Isoelectric Point8.5
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
- DownloadInstruction Manual
200µg 1mg 5mg
For more details, please contact local distributors! US$ 480 FREE TRIAL
For more details, please contact local distributors! US$ 960 FREE TRIAL
For more details, please contact local distributors! US$ 2880 FREE TRIAL
For more details, please contact local distributors! US$ 7200 FREE TRIAL
For more details, please contact local distributors!
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
- Endotoxin Removal Kit
- BCA Protein Quantification Kit
- Protein Labeling Customized Service
- Recombinant Protein Customized Service
- Monoclonal Antibody Customized Service
- Polyclonal Antibody Customized Service
- Protein Activity Test Experiment Service
- Immunoprecipitation (IP) Experiment Service
- Endotoxin Removal Kit II
|Journal of Orthopaedic Research||Promotion of bone formation by naringin in a titanium particle-induced diabetic murine calvarial osteolysis model PubMed: 19824055|
|World Journal of Gastroenterology||Connective tissue growth factor hammerhead ribozyme attenuates human hepatic stellate cell function PubMed: PMC2726461|
|PLos One||Activation of JNK Signaling Mediates Connective Tissue Growth Factor Expression and Scar Formation in Corneal Wound Healing Plosone: 0032128|
|Clinical Biochemistry||Clinical significance of inflammatory and fibrogenic cytokines in diabetic nephropathy ScienceDirect: S0009912012000987|
|The Journal of Heart and Lung Transplantation||Connective tissue growth factor (CTGF/CCN2): A protagonist in cardiac allograft vasculopathy development? PubMed: S1053249812010121|
|Biomedical and Environmental Sciences||The Intervention Effect of Rosiglitozone in Ovarian Fibrosis of PCOS Rats Besjournal: Source|
|Disease Markers||Concentrations of connective tissue growth factor in patients with nonalcoholic fatty liver disease: Association with liver fibrosis PubMed: 22846210|
|World Journal of Gastroenterology||Clinical significance of connective tissue growth factor in hepatitis B virus-induced hepatic fibrosis PubMed: PMC3351780|
|Journal of ethnopharmacology||Multitargeted protective effect of Abacopteris penangiana against carrageenan-induced chronic prostatitis in rats. Pubmed: 24211397|
|Radiation Oncology||Cytokine levels as biomarkers of radiation fibrosis in patients treated with breast radiotherapy Ro-journal: Source|
|PLoS One.||Knock Out of S1P3 Receptor Signaling Attenuates Inflammation and Fibrosis in Bleomycin-Induced Lung Injury Mice Model Pubmed:Pmc4157792|
|European Journal of Heart Failure||Connective tissue growth factor and cardiac diastolic dysfunction: human data from the Taiwan Diastolic Heart Failure Registry and molecular basis by cellular and animal models Pubmed:24464932|
|Bone||Connective Tissue Growth Factor is a Target of Notch Signaling in Cells of the Osteoblastic Lineage Pubmed:24792956|
|American Journal of Pathology||Disruption of collagen homeostasis can reverse established age-related myocardial fibrosis Pubmed:25701883|
|J Gastroenterol||Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis PubMed: 26190501|
|Life Sciences||Suppression of connective tissue growth factor mediates the renoprotective effect of Sitagliptin rather than Pioglitazone in type 2 diabetes mellitus Pubmed:27049870|
|International Journal of Molecular Sciences||TGF-β and Physiological Root Resorption of Deciduous Teeth. pubmed:28035998|
|Inflammation Research||Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy pubmed:27516211|
|Heart & Vessels||Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR pubmed:28004175|
|British Journal of Ophthalmology||The relationship between anti-vascular endothelial growth factor and fibrosis in proliferative retinopathy: clinical and laboratory evidence pubmed:27531356|
|Pathophysiology||Molecular mechanisms underlying fibrosis and elastin destruction in childhood interstitial lung diseases pubmed:27686729|
|Catalog No.||Related products for research use of Sus scrofa; Porcine (Pig) Organism species||Applications (RESEARCH USE ONLY!)|
|RPA010Po01||Recombinant Connective Tissue Growth Factor (CTGF)||Positive Control; Immunogen; SDS-PAGE; WB.|
|PAA010Po01||Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)||WB; IHC; ICC; IP.|
|LAA010Po71||Biotin-Linked Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)||WB; IHC; ICC.|
|MAA010Po21||Monoclonal Antibody to Connective Tissue Growth Factor (CTGF)||WB; IHC; ICC; IP.|
|SEA010Po||ELISA Kit for Connective Tissue Growth Factor (CTGF)||Enzyme-linked immunosorbent assay for Antigen Detection.|
|SCA010Po||CLIA Kit for Connective Tissue Growth Factor (CTGF)||Chemiluminescent immunoassay for Antigen Detection.|
|PSA010Po01||Antibody Pair for Connective Tissue Growth Factor (CTGF)||ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.|
|KSA010Po01||ELISA Kit DIY Materials for Connective Tissue Growth Factor (CTGF)||Main materials for "Do It (ELISA Kit) Yourself".|