Polyclonal Antibody to S-Adenosyl Methionine (SAM)

SAMe; SAM-e; S-Adenosylmethionine; S-(5'-Adenosyl)-L-Methionine Chloride

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against SAM. It has been selected for its ability to recognize SAM in ELISA and CLIA.

USAGE

Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Cell Death and Disease Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation pubmed:27929536
PLoS One Attenuated expression of MTR in both prenatally androgenized mice and women with the hyperandrogenic phenotype of PCOS pubmed:29232372vvvv
Microbial Cell Factories Metabolic engineering of Acremonium chrysogenum for improving cephalosporin C production independent of methionine stimulation Pubmed:29879990
Cell Metabolism Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation 33798471
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