Polyclonal Antibody to Salusin Beta (SALb)

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against SALb. It has been selected for its ability to recognize SALb in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Journal of Maternal-Fetal and Neonatal Medicine Serum levels of apelin, salusin-alpha, and salusin-beta in normal pregnancy and preeclampsia Informa: 14767058.2012.660221
Peptides The bioactive peptides salusins and apelin–36 are produced in human arterial and venous tissues and the changes of their levels during cardiopulmonary bypass PubMed: 22884920
Department of Medical Biochemistry and Clinical Biochemistry Presence of adropin, nesfatin-1, apelin-12, ghrelins and salusins peptides in the milk, cheese whey and plasma of dairy cows ScienceDirect: S0196978113000533
European Journal of Obstetrics & Gynecology and Reproductive Biology Association of low maternal levels of salusins with gestational diabetes mellitus and with small-for-gestational-age fetuses. PubMed: 23178004
Biotech Histochem. Serum concentration and kidney expression of salusin-α and salusin-β in rats with metabolic syndrome induced by fructose. PubMed: 23244237
Gynecological Endocrinology, Salusins, newly identified regulators of hemodynamics and mitogenesis, increase in polycystic ovarian syndrome. PubMed: 22827297
Peptides Concentrations of preptin, salusins and hepcidins in plasma and milk of lactating women with or without gestational diabetes mellitus ScienceDirect: S0196978113003100
Biotechnic & Histochemistry Salusin-alpha and -beta expression in heart and aorta with and without metabolic syndrome Com:Source
Med Sci Monit. Brain, Liver, and Serum Salusin-alpha and-beta Alterations in Sprague-Dawley Rats with or Without Metabolic Syndrome Pubmed:Pmc4136931
Acta Physiologica Superoxide anions involved in sympathoexcitation and pressor effects of salusin-β in paraventricular nucleus in hypertensive rats Pubmed:24304512
Pediatr Nephrol. Is the serum level of salusin-β associated with hypertension and atherosclerosis in the pediatric population? Pubmed:25245503
European Journal of Dermatology Serum salusin-α and salusin-β levels in patients with psoriasis PubMed: 26055619
J Investig Med Serum Salusin-β Levels Are Associated With the Presence and Severity of Coronary Artery Disease PubMed: 25730454
Genet Test Mol Biomarkers.  Serum Salusin-β Levels Are Correlated with Slow Coronary Flow. Pubmed:27227272
Sci Rep.  Silencing salusin-β attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats. pubmed:28230187
Cell Death Dis. Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy pubmed:28333148
Oxidative Medicine and Cellular Longevity Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma 10.1155:2017
International Journal Of Cardiology Silencing salusin β ameliorates heart failure in aged spontaneously hypertensive rats by ROS-relative MAPK/NF-κB pathways in the paraventricular nucleus Pubmed: 30581101
Multiple Sclerosis and Related Disorders Increased level of Plasma Salusin-α and Salusin-β in patients with Multiple Sclerosis Pubmed: 30738876
cardiology in the young Salusin-α levels are negatively correlated with diastolic blood pressure in children with obesity Pubmed: 31486354
Redox Biology Salusin-β mediates tubular cell apoptosis in acute kidney injury: Involvement of the PKC/ROS signaling pathway Pubmed: 31884071
Journal of international medical research Salusin-β is superior to salusin-α as a marker for evaluating coronary atherosclerosis Pubmed: 32054363
cardiovascular drugs and therapy A TOR2A Gene Product: Salusin-β Contributes to Attenuated Vasodilatation of Spontaneously Hypertensive Rats. Pubmed: 32458319
Serum level of salusin β as an indicator of metabolic disorders in Acute Lymphoblastic Leucaemia and Wilms Tumour survivors
Mol Med Rep Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner 34296310
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