≡

Polyclonal Antibody to Orexin A (OXA)

Hypocretin-1

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against OXA. It has been selected for its ability to recognize OXA in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Frontiers in Neurology Neuro-Glial and Systemic Mechanisms of Pathological Responses in Rat Models of Primary Blast Overpressure Compared to “Composite” Blast PubMed: PMC3275793
Neurological Sciences Pentylenetetrazol-induced seizures are exacerbated by sleep deprivation through orexin receptor-mediated hippocampal cell proliferation Pubmed: 23852314
Peptides Orexin-A-induced ERK1/2 activation reverses impaired spatial learning and memory in pentylenetetrazol-kindled rats via OX1R-mediated hippocampal neurogenesis. Pubmed: 24321199
Alcohol Alcohol Orexin in Patients with Alcohol Dependence Treated for Relapse Prevention: A Pilot Study PubMed: 26597795
Indian Journal of Medical Research and Pharmaceutical Sciences Evaluation of Antidiabetic And Insulintropic Potential of Nigella Sativa Seeds Water Extract and /or Alpha Lipoic Acid in Type 2 Diabetic Rats Issues%20Pdf: Vol.2
J Clin Res Pediatr Endocninol Correlation of Brain Neuropeptide (Nesfatin-1 and Orexin-A) Concentrations with Anthropometric and Biochemical Parameters in Malnourished Children PubMed: 26831553
Neural Regen Res Resuscitation therapy for traumatic brain injury-induced coma in rats: mechanisms of median nerve electrical stimulation PubMed: 26170820
Mol Med Rep Wake-promoting actions of median nerve stimulation in TBI-induced coma: An investigation of orexin-A and orexin receptor 1 in the hypothalamic region PubMed: 26059340
Mol Neurobiol Application of the Co-culture Membrane System Pointed to a Protective Role of Catestatin on Hippocampal Plus Hypothalamic Neurons Exposed to Oxygen and Glucose Deprivation article:10.1007
Neural Regeneration Research Wake-promoting effects of vagus nerve stimulation after traumatic brain injury: upregulation of orexin-A and orexin receptor type 1 expression in the prefrontal … Pubmed:29557373
Journal of Translational Medicine Recurrent circadian fasting (RCF) improves blood pressure, biomarkers of cardiometabolic risk and regulates inflammation in men Pubmed: 31426866
iraqi journal of science Relationship Between Orexin-A and Insulin Resistance in Patients with Type 2 Diabetes Mellitus
Brain Sci Changes in the Orexin System in Rats Exhibiting Learned Helplessness Behaviors 34942932
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPA607Mu01 Recombinant Orexin A (OXA) Positive Control; Immunogen; SDS-PAGE; WB.
PAA607Mu01 Polyclonal Antibody to Orexin A (OXA) WB; IHC; ICC; IP.