Monoclonal Antibody to Vanin 1 (VNN1)

Pantetheinase; Pantetheine hydrolase; Tiff66; Vascular non-inflammatory molecule 1

SPECIFITY

The antibody is a mouse monoclonal antibody raised against VNN1. It has been selected for its ability to recognize VNN1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Toxicology Vanin-1; a potential biomarker for nephrotoxicant-induced renal injury ScienceDirect: S0300483X11003234
Journal of Pharmacology and Experimental Therapeutics Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury Aspet: 192807
J Pharmacol Exp Ther Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury. PubMed: 22399813
Journal of Applied Toxicology Early detection of renal injury using urinary vanin-1 in rats with experimental colitis PubMed: 23307618
Iranian Journal of Health and Physical Activity Effects of Exercise and Ferula Gummosa on Apelin of Cardiac and Kidney Tissues in L-NAME induced Hypertension in Rats Jm.um: Source
Platelets Value of vanin-1 assessment in adult patients with primary immune thrombocytopenia Pubmed: 23534352
Journal of Applied Toxicology Early detection of renal injury using urinary vanin-1 in rats with experimental colitis. Pubmed: 23307618
Diabetes & Vascular Disease Research Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats Sagepub:Source
Food Chem Toxicol. The effect of activated charcoal on adenine-induced chronic renal failure in rats Pubmed:24412558
Hypertension Research Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake PubMed: 26376947
Inflammation Citrate Attenuates Adenine-Induced Chronic Renal Failure in Rats by Modulating the Th17/Treg Cell Balance PubMed: 26253296
Toxicology Early prediction of cisplatin-induced nephrotoxicity by urinary vanin-1 in patients with urothelial carcinoma Pubmed:27317936
J Biomed Mater Res A Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice Pubmed:26850371
APMIS Citrate attenuates vascular calcification in chronic renal failure rats. pubmed:28332248
Clin Exp Pharmacol Physiol. Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats. pubmed:29027259
Cellular Physiology and Biochemistry Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats … Pubmed:29550811
International Journal of Molecular Sciences Vanin-1 in Renal Pelvic Urine Reflects Kidney Injury in a Rat Model of Hydronephrosis Pubmed: 30332759
International Journal of Molecular Sciences Involvement of Vanin-1 in Ameliorating Effect of Oxidative Renal Tubular Injury in Dahl-Salt Sensitive Rats Pubmed: 31514290
The Journal of Clinical Hypertension homepage Urinary vanin‐1 associated with chronic kidney disease in hypertensive patients: A pilot study Pubmed: 32869948
J Clin Hypertens Association of urinary vanin©\1 with kidney function decline in hypertensive patients 34029440
Plasma vanin-1 as a novel biomarker of sepsis for trauma patients: a prospective multicenter cohort study 33624223
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPC598Hu02 Recombinant Vanin 1 (VNN1) Positive Control; Immunogen; SDS-PAGE; WB.
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